Clinical pharmacology of bronchodilator medications

DM Williams, BK Rubin - Respiratory Care, 2018 - rc.rcjournal.com
Obstructive lung diseases, including asthma and COPD, are characterized by air-flow
limitation. Bronchodilator therapy can often decrease symptoms of air-flow obstruction by …

Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - ASPET
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

Pharmacology and therapeutics of bronchodilators

M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

An update on bronchodilators in Phase I and II clinical trials

M Cazzola, P Rogliani, A Segreti… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Inhaled bronchodilators are the mainstay of the current management of COPD
at all stages of the disease, and are critical in the symptomatic management of asthma …

Current and novel bronchodilators in respiratory disease

D Spina - Current Opinion in Pulmonary Medicine, 2014 - journals.lww.com
Novel long-acting β 2-agonists (eg indacaterol, vilanterol, olodaterol and carmoterol) and
muscarinic antagonists (eg tiotropium, aclidinium, glycopyrronium and umeclidinium …

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma?

D Price, L Fromer, A Kaplan, T Van Der Molen… - NPJ primary care …, 2014 - nature.com
Despite current guidelines and the range of available treatments, over a half of patients with
asthma continue to suffer from poor symptomatic control and remain at risk of future …

Emerging inhaled bronchodilators: an update

M Cazzola, MG Matera - European Respiratory Journal, 2009 - Eur Respiratory Soc
Bronchodilators remain central to the symptomatic management of chronic obstructive
pulmonary disease and asthma, and, for this reason and also because the patent protection …

β2-Agonist Therapy in Lung Disease

M Cazzola, CP Page, P Rogliani… - American journal of …, 2013 - atsjournals.org
β2-Agonists are effective bronchodilators due primarily to their ability to relax airway smooth
muscle (ASM). They exert their effects via their binding to the active site of β2-adrenoceptors …

Long-acting beta-agonists and their association with inhaled corticosteroids in COPD

L Fuso, N Mores, S Valente, M Malerba… - Current medicinal …, 2013 - ingentaconnect.com
Inhaled bronchodilators, including beta2-agonists and antimuscaric receptor antagonists,
are the mainstay of pharmacotherapy in chronic obstructive pulmonary disease (COPD). The …

Advances in adrenergic receptors for the treatment of chronic obstructive pulmonary disease: 2023 update

MG Matera, B Rinaldi, L Calzetta… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Strong scientific evidence and large experience support the use of β2-agonists
for the symptomatic alleviation of COPD. Therefore, there is considerable effort in …