Apparent changes in the epidemiology and severity of multiple sclerosis

N Koch-Henriksen, M Magyari - Nature Reviews Neurology, 2021 - nature.com
Multiple sclerosis (MS) is an immunological disease that causes acute inflammatory lesions
and chronic inflammation in the CNS, leading to tissue damage and disability. As awareness …

The changing course of multiple sclerosis: rising incidence, change in geographic distribution, disease course, and prognosis

M Magyari, PS Sorensen - Current opinion in neurology, 2019 - journals.lww.com
An increased interest in population-based registries and databases will provide more valid
epidemiological measures and observational studies conducted in well-defined study …

A systematic review of modifiable risk factors in the progression of multiple sclerosis

S Hempel, GD Graham, N Fu, E Estrada… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: The presenting symptoms and rate of progression of multiple sclerosis (MS)
are very heterogeneous. The diverse clinical manifestations and the clinical course of the …

Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions

EM Frohman, M Filippi, O Stuve, SG Waxman… - Archives of …, 2005 - jamanetwork.com
Major advancements have been achieved in our ability to diagnose multiple sclerosis (MS)
and to commence treatment intervention with agents that can favorably affect the disease …

What is multiple sclerosis?

R Marcus - Jama, 2022 - jamanetwork.com
Who Is Affected by and at Risk of MS? About 900 000 people in the US have MS. Onset of
symptoms typically occurs at age 20 to 30 years. Women are nearly 3 times more likely to …

Multiple sclerosis: an immune or neurodegenerative disorder?

BD Trapp, KA Nave - Annu. Rev. Neurosci., 2008 - annualreviews.org
Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human
central nervous system. The clinical disease course is variable, usually starts with reversible …

Multiple sclerosis: a practical overview for clinicians

K Rejdak, S Jackson, G Giovannoni - British medical bulletin, 2010 - academic.oup.com
Multiple sclerosis (MS) is the commonest disabling neurological condition to afflict young
adults and therefore has a high social burden. Over several decades, there has been a …

[PDF][PDF] An overview of the history, pathophysiology, and pharmacological interventions of multiple sclerosis

IM Dighriri, AA Aldalbahi, F Albeladi, AA Tahiri… - Cureus, 2023 - cureus.com
Multiple sclerosis (MS) is an immune-inflammatory disease that attacks and damages
myelinated axons in the central nervous system (CNS) and causes nontraumatic …

[HTML][HTML] Treatment strategies for multiple sclerosis: when to start, when to change, when to stop?

A Gajofatto, MD Benedetti - World Journal of Clinical Cases: WJCC, 2015 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a chronic inflammatory condition of the central nervous system
determined by a presumed autoimmune process mainly directed against myelin …

A comprehensive review on the treatment approaches of multiple sclerosis: currently and in the future

M Gholamzad, M Ebtekar, MS Ardestani, M Azimi… - Inflammation …, 2019 - Springer
Background Multiple sclerosis (MS) is a chronic and autoimmune disease of the central
nervous system (CNS), mainly characterized by inflammatory demyelination, which …