The control and elimination of malaria caused by Plasmodium vivax both represent a great
challenge due to the biological aspects of the species. Gametocytes are the forms …

Background The use of molecular techniques has put in the spotlight the existence of a large
mass of malaria sub-microscopic infections among apparently healthy populations. These …

Significant progress toward the control of malaria has been achieved, especially regarding
Plasmodium falciparum infections. However, the unique biology of Plasmodium vivax …

Understanding the life cycle of Plasmodium vivax is fundamental for developing strategies
aimed at controlling and eliminating this parasitic species. Although advances in omic …

Background The study of the biology, transmission and pathogenesis of Plasmodium vivax
is hindered due to the lack of a robustly propagating, continuous culture of this parasite. The …

Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Establishment of a continuous line of Plasmodium vivax parasite is crucial to understand the
parasite's biology; however, this has not yet been achieved. Beginning in the 19th century …

The recent research efforts to establish a Plasmodium vivax continuous, long-term blood-
stage culture have focused on the ideal host cell type. However, this is only part of the story …

Abstract Background The production of Plasmodium gametocytes in vitro is a real challenge.
Many protocols have been described, but few have resulted in the production of viable and …

Microscopic detection of Plasmodium vivax gametocytes, the sexual life stage of this malaria
parasite, is insensitive because P. vivax parasitaemia is low. To detect and quantify …