During the initiation of invasive aspergillosis, inhaled Aspergillus fumigatus conidia are
deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While …

Background The airway epithelium is the first barrier interacting with Aspergillus fumigatus
conidia after their inhalation, suggesting that this structure functions as point of entry of this …

Invasive pulmonary aspergillosis is acquired through inhalation of conidia. Little is known
about early interactions between Aspergillus fumigatus conidia and alveolar epithelial cells …

The immunocompromised airways are susceptible to infections caused by a range of
pathogens which increases the opportunity for polymicrobial interactions to occur …

Aspergillus fumigatus is a ubiquitous fungal pathogen capable of causing multiple
pulmonary diseases, including invasive aspergillosis, chronic necrotizing aspergillosis …

Invasive aspergillosis is initiated when Aspergillus fumigatus adheres to and invades the
pulmonary epithelial cells that line the airways and alveoli. To gain deeper insight into how …

The airway exposure to Aspergillus fumigatus spores (AFsp) is associated with an
inflammatory response, potentially leading to allergic and/or chronic pulmonary …

Aspergillus spp., especially A. fumigatus (Af) can colonize the airways and the lungs with
localized underlying conditions and further invade the surrounding lung tissues, even in …

Background Invasive aspergillosis, which is mainly caused by the fungus Aspergillus
fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by …

Several pathogenic fungal organisms enter eukaryotic cells and manipulate the host cell
environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic …