Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder
associated with mechanical stress and aging but also a 'metabolic syndrome'in which …

Osteoarthritis (OA) is an age-related degenerative disease comprising the main reason of
handicap in the Western world. Interestingly, to date, there are neither available biomarkers …

Methods OA patterns were studied in 809 patients with knee or hip joint replacement due to
OA in 4 hospitals in southwest Germany. Participants had a standardized interview and …

Cholesterol homeostasis plays a significant role in skeletal development and the
dysregulation of cholesterol-related mechanism has been shown to be involved in the …

Objective Hypercholesterolaemia, a risk factor for atherosclerosis (ATH), has been
suggested to have a role in the development of osteoarthritis (OA). To test this hypothesis …

Osteoarthritis (OA) has become a major public health problem not only because of its
increasing prevalence worldwide but also because of its frequent association with …

There is increasing evidence that low-density lipoprotein (LDL) cholesterol plays a role in
the pathology of OA. Specifically, oxidized LDL (oxLDL), which has been shown to play an …

In recent years, several papers that report an association between atherosclerosis (AS) and
osteoarthritis (OA) have been published. Studying this relation is, however, not a sinecure …

Introduction Environmental exposures, including smoking, hormone-related factors, and
metabolic factors, have been implicated in the etiology of rheumatoid arthritis (RA). A …

Objective A relation between osteoarthritis (OA) and increased cholesterol levels is
apparent. In the present study we investigate OA pathology in apolipoprotein E (ApoE) …