Currently, no reliable predictors of cognitive impairment in Parkinson's disease exist. We
hypothesized that microstructural changes at grey matter T1-weighted MRI and diffusion …

Abstract See Gratwicke and Foltynie (doi: 10.1093/brain/awx333) for a scientific commentary
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …

Objectives Cholinergic dysfunction plays a prominent role in cognitive impairment in
Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline …

Objective A major contributor to dementia in Parkinson disease (PD) is degeneration of the
cholinergic basal forebrain. This study determined whether cholinergic nucleus 4 (Ch4) …

Objective The underlying pathology of brain leading to cognitive impairment in Parkinson's
disease (PD) remains poorly understood. The aim of our study was to test the hypothesis …

Background Previous MRI studies have investigated cortical or subcortical grey matter
changes in patients with Parkinson's disease (PD), yielding inconsistent findings between …

Cognitive deficits in Alzheimer's disease, specifically amnestic (memory dominant) deficits,
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …

The current review summarizes the current knowledge on longitudinal cortical and
subcortical grey and white matter MRI findings assessed using T1-weighted and one-tensor …

Diffusion magnetic resonance imaging is increasingly used as a non-invasive method to
investigate white matter structure in neurological and neuropsychiatric disease. However …

Mild cognitive impairment in Parkinson's disease is associated with progression to dementia
(Parkinson's disease dementia) in a majority of patients. Determining structural imaging …