The use of cell culture to characterize bone and tooth mineralization has blossomed, thanks
to the development of genetically engineered animals with altered bone and tooth …

This marks the first of a new series of special issues of Calcified Tissue International,
planned by the Editorial Board, which will present original articles on a particular topic or …

In the past few years biomimetics has come to calcified tissues. Biomimetics, a science
based on biological recognition, is based on the idea that biological systems store and …

Well-characterized human bone cell cultures have been regarded as auseful tool to study
bone control mechanisms and also to analysebone/biomaterials interactions. In the present …

Background The pulp contains a resident population of stem cells which can be stimulated
to differentiate in order to repair the tooth by generating a mineralized extracellular matrix …

Osteoblast cultures can be used to investigate the mechanisms of bone formation, to probe
the cellular and molecular basis of bone disease, and to screen for potential therapeutic …

A sufficient amount of easily obtained and well-characterized osteoblastic cells is a useful
tool to study biomaterial/cell interactions essential for bone tissue engineering. Osteoblastic …

Within the past year the importance of heterogeneous nucleation in bone mineralization has
been revealed by studies from different fields of calcified tissue research. These new …

This paper describes the isolation, culture and staining of primary osteoblasts from neonatal
rodents and human samples. The calvaria and long-bone assays allow direct measurement …

Biomineralization is the process by which mineral crystals are deposited in an organized
fashion in the matrix (either cellular or extracellular) of living organisms. Over the past 25 …