Background Recently, we clarified at the molecular level novel chromosomal translocation t
(14; 14)(q11; q32) in a case of Sézary syndrome, which caused a rearrangement from …

Figure 1. Functional significance of PP2R5E in AML cells.(A) Western blot and densitometric
analysis of the expression levels of PPP2R5E in 16 AML patient samples.(B) MTS assay …

Recently, alterations in the expression pattern of PPP2R5C associated with malignant
transformation have been characterized, and PPP2R5C overexpression was demonstrated …

Recently, the PTEN/MMAC1 gene encoding a protein phosphatase (PP) and the PPP2R1B
gene encoding a regulatory subunit of PP2A have been identified as being genetically …

Abstract Mutation of PPP2R1A has been observed at high frequency in endometrial serous
carcinomas but at low frequency in ovarian clear cell carcinoma. However, the biological …

Deletion of chromosome bands 1 Iq22-q23 is one of the most common structural
chromosome alterations in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma …

Recent studies have shown that PPP1R14B was highly expressed in tumor tissues and
patients with high expression of PPP1R14B had poor survival rates. However, the function …

Abstract PPP2R2C encodes a gamma isoform of the subunit B55 subfamily, which is a
regulatory subunit of Protein phosphatase type 2A (PP2A). Our study shows that PPP2R2C …

Protein phosphatase 2, regulatory subunit B (B56), alpha isoform (PPP2R5A) is one of the
regulatory subunits of the protein phosphatase 2A (PP2A), which is a major member of …

Recently, we found nonsense and missense mutations of the PPP1R3 (protein phosphatase
1, regulatory subunit 3) gene in diverse human cancer cell lines and primary lung …