The global burden of fracture-related infection: can we do better?

WJ Metsemakers, TF Moriarty… - The Lancet Infectious …, 2024 - thelancet.com
Fracture-related infection is a major complication related to musculoskeletal injuries that not
only has important clinical consequences, but also a substantial socioeconomic impact …

The epidemiology of fracture-related infections in Germany

N Walter, M Rupp, S Lang, V Alt - Scientific Reports, 2021 - nature.com
The epidemiology of fracture-related infection (FRI) is unknown, which makes it difficult to
estimate future demands and evaluate progress in infection prevention. Therefore, we aimed …

[HTML][HTML] Pathogenesis and management of fracture-related infection

M Depypere, M Morgenstern, R Kuehl… - Clinical Microbiology …, 2020 - Elsevier
Background Both fracture-related infections (FRIs) and periprosthetic joint infections (PJIs)
include orthopaedic implant-associated infections. However, key aspects of management …

Global forum: the burden of bone and joint infections: a growing demand for more resources

KN Malizos - JBJS, 2017 - journals.lww.com
The rate and severity of septic complications following joint replacement surgery and the
incidence of posttraumatic infections are projected to increase at a faster pace because of a …

Management of fracture-related infection in low resource settings: how applicable are the current consensus guidelines?

EK Tissingh, L Marais, A Loro, D Bose… - EFORT open …, 2022 - eor.bioscientifica.com
The global burden of fracture-related infection (FRI) is likely to be found in countries with
limited healthcare resources and strategies are needed to ensure the best available practice …

Recommendations for systemic antimicrobial therapy in fracture-related infection: a consensus from an international expert group

M Depypere, R Kuehl, WJ Metsemakers… - … of orthopaedic trauma, 2020 - journals.lww.com
Fracture-related infection (FRI) is a major complication in musculoskeletal trauma and one of
the leading causes of morbidity. Standardization of general treatment strategies for FRI has …

Clinical practice in prevention of fracture-related infection: An international survey among 1197 orthopaedic trauma surgeons

J Puetzler, C Zalavras, TF Moriarty, MHJ Verhofstad… - Injury, 2019 - Elsevier
Introduction Open fractures are still a challenge in orthopaedic trauma surgery, and
compared to closed fractures, the rate of complications including fracture-related infection …

Fracture-related infection

S Baertl, WJ Metsemakers, M Morgenstern… - Bone & Joint …, 2021 - boneandjoint.org.uk
Background Fracture-related infection (FRI) carries a substantial burden of disease and
socio-economic costs. 1-3 The incidence of FRI is 1% to 2% in closed fractures and can …

[HTML][HTML] The effect of guideline-based antimicrobial therapy on the outcome of fracture-related infections (EAT FRI Study)

R Corrigan, J Sliepen, RJ Rentenaar, F IJpma… - Journal of Infection, 2023 - Elsevier
Aim This study investigated the compliance with a guideline-based antibiotic regimen on the
outcome of patients surgically treated for a fracture-related infection (FRI). Method In this …

Osteomyelitis

DP Lew, FA Waldvogel - The Lancet, 2004 - thelancet.com
Bone and joint infections are painful for patients and frustrating for both them and their
doctors. The high success rates of antimicrobial therapy in most infectious diseases have not …