The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

Ruthenium complexes: an emerging ground to the development of metallopharmaceuticals for cancer therapy

M Abid, F Shamsi, A Azam - Mini Reviews in Medicinal …, 2016 - ingentaconnect.com
GLOBOCAN 2012 estimates 14.1 million new cancer cases and 8.2 million cancer-related
deaths worldwide. Cancer is rapidly becoming a major public health concern in India as …

Ruthenium complexes as anticancer agents

I Kostova - Current medicinal chemistry, 2006 - ingentaconnect.com
Cancer is one of the major cases of death in the world. Current treatment of cancer is limited
to surgery, radiotherapy, and the use of cytotoxic agents, despite their well known side …

An overview of advancement of organoruthenium (II) complexes as prospective anticancer agents

M Bashir, IA Mantoo, F Arjmand, S Tabassum… - Coordination Chemistry …, 2023 - Elsevier
The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

Anticancer activities of mononuclear ruthenium (II) coordination complexes

WM Motswainyana, PA Ajibade - Advances in Chemistry, 2015 - Wiley Online Library
Ruthenium compounds are highly regarded as potential drug candidates. The compounds
offer the potential of reduced toxicity and can be tolerated in vivo. The various oxidation …

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

A Bergamo, G Sava - Dalton Transactions, 2011 - pubs.rsc.org
Ruthenium anticancer drugs have attracted an increasing interest in the last 20 years and
two of them have entered clinical trials. Compared to platinum drugs, the complexes based …

Recent developments on other platinum metal complexes as target-specific anticancer therapeutics

TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

Detailed account on activation mechanisms of ruthenium coordination complexes and their role as antineoplastic agents

M Pal, U Nandi, D Mukherjee - European Journal of Medicinal Chemistry, 2018 - Elsevier
Ruthenium (Ru) complexes are known for their promising anticancer activity presumably
due to octahedral coordination geometry, slow ligand exchange rate, the range of different …

Editorial of special issue ruthenium complex: The expanding chemistry of the ruthenium complexes

I Dragutan, V Dragutan, A Demonceau - Molecules, 2015 - mdpi.com
Molecules | Free Full-Text | Editorial of Special Issue Ruthenium Complex: The Expanding
Chemistry of the Ruthenium Complexes Next Article in Journal The Guareschi Pyridine …

Ruthenium (II)–arene complexes as anti-metastatic agents, and related techniques

C Sonkar, S Sarkar, S Mukhopadhyay - RSC medicinal chemistry, 2022 - pubs.rsc.org
With the discovery of cisplatin, a vast area of applications of metallodrugs in cancer
treatment was opened but due to the side effects caused by the cisplatin complexes …