Eco-friendly deep eutectic solvents contribute to improving the separation of isoquinoline alkaloids in supercritical fluid chromatography

ZM Jiang, WJ Liu, Y Li, J Liu, HY Wang… - ACS Sustainable …, 2020 - ACS Publications
In this work, for the first time, 10 isoquinoline alkaloids (IQAs) were separated and
determined by supercritical fluid chromatography (SFC) utilizing eco-friendly deep eutectic …

Supercritical fluid chromatography based on reversed-phase/ion chromatography mixed-mode stationary phase for separation of spirooxindole alkaloids

Q Fu, W Dong, D Ge, Y Ke, Y Jin - Journal of Chromatography A, 2023 - Elsevier
The present paper illustrates the versatility of the supercritical fluid chromatography (SFC)
since, for the first time, four spirooxindole alkaloids (SOAs) including two pairs of isomers …

Ion pair-based mobile phase additives to improve the separation of alkaloids in supercritical fluid chromatography

ZX Yue, YX Gu, TC Yan, MH Li, H Zheng… - Journal of Pharmaceutical …, 2022 - Elsevier
In this study, a supercritical fluid chromatography (SFC) method based on ion pair reagents
was used to separate alkaloids. The chromatographic parameters, including the stationary …

Sustainable approaches for the study of alkaloids from plants using supercritical fluid-based processes

J Pavón-Pérez, A Vallejos-Almirall, C Agurto-Muñoz… - Green …, 2022 - pubs.rsc.org
Plant alkaloids are natural secondary metabolites that have attracted great interest in the
development of drugs for therapeutic applications due to their diverse bioactivities. For the …

First proof-of-concept of UC/HILIC for extending the versatility of the current art of supercritical fluid separation

L Si-Hung, Y Izumi, T Bamba - Analytica Chimica Acta, 2023 - Elsevier
Abstract Supercritical Fluid Chromatography (SFC), a high-throughput separation technique,
has been widely applied as a promising routine method in pharmaceutical, pesticides, and …

Synthesis and evaluation of aromatic stationary phases based on linear solvation energy relationship model for expanded application in supercritical fluid …

D Ge, J Yang, Z Yu, J Lu, Y Chen, Y Jin, Y Ke… - … of Chromatography A, 2024 - Elsevier
In the last decade, the separation application based on aromatic stationary phases has been
demonstrated in supercritical fluid chromatography (SFC). In this paper, four aromatic …

Advanced development of supercritical fluid chromatography in herbal medicine analysis

M Chen, SS Wen, R Wang, QX Ren, CW Guo, P Li… - Molecules, 2022 - mdpi.com
The greatest challenge in the analysis of herbal components lies in their variety and
complexity. Therefore, efficient analytical tools for the separation and qualitative and …

The use of ionic liquid as a mobile phase modifier in analytical supercritical fluid chromatography for the separation of flavonoids

W Gao, X Dong, R Wang, XG Liu, P Li, H Yang - RSC advances, 2016 - pubs.rsc.org
Due to the low viscosity of carbon dioxide, supercritical-fluid chromatography (SFC) allows
higher flow rates with lower back pressure. Generally, analytical SFC could provide much …

Alkaloids analysis using off-line two-dimensional supercritical fluid chromatography× ultra-high performance liquid chromatography

K Li, Q Fu, H Xin, Y Ke, Y Jin, X Liang - Analyst, 2014 - pubs.rsc.org
In this study, an off-line two-dimensional (2-D) supercritical fluid chromatography (SFC)×
ultra-high performance liquid chromatography (UHPLC) method with high orthogonality was …

Supercritical fluid chromatography–a technical overview and its applications in medicinal plant analysis: An update covering 2012–2018

P He, Y Zhang, Y Zhou, G Li, J Zhang, X Feng - Analyst, 2019 - pubs.rsc.org
Medicinal plants with complex matrices are endowed with a wide scope of biological
activities. The separation, quantification, characterization and purification of bioactive …