Background The effects of constant-current deep brain stimulation (DBS) have not been
studied in controlled trials in patients with Parkinson's disease. We aimed to assess the …

Background Deep brain stimulation (DBS) of the subthalamic nucleus is an established
therapeutic option for managing motor symptoms of Parkinson's disease. We conducted a …

Background High-frequency deep brain stimulation (DBS) with a single electrical source is
effective for motor symptom relief in patients with Parkinson's disease. We postulated that a …

Background Neurostimulation of the subthalamic nucleus reduces levodopa-related motor
complications in advanced Parkinson's disease. We compared this treatment plus …

Objective: To examine objectively the clinical effects of subthalamic nucleus (STN) deep
brain stimulation (DBS) in advanced PD. Methods: Our initial seven consecutive patients …

OBJECTIVE: To prospectively assess the impact of subthalamic nucleus (STN) deep brain
stimulation (DBS) at 12 months after surgery in a series of 100 consecutive patients treated …

Electrical stimulation of the subthalamic nucleus is an established treatment for patients with
advanced Parkinson's disease with pharmacologically unresponsive fluctuations. Compared …

This study compares the effects on motor symptoms between conventional deep brain
stimulation (cDBS) and closed-loop adaptive deep brain stimulation (aDBS) in patients with …

BACKGROUND Deep brain stimulation (DBS) has been established as an alternative
approach for the treatment of advanced Parkinson's disease (PD). Recently, the subthalamic …

Objective To assess the 10-year motor outcome of deep brain stimulation of the subthalamic
nucleus (STN-DBS) in patients with Parkinson disease (PD). Design Patients with PD with …