GRPr Theranostics: current status of imaging and therapy using GRPr targeting radiopharmaceuticals
J Kurth, M Potratz, M Heuschkel… - Nuklearmedizin …, 2022 - thieme-connect.com
Addressing molecular targets, that are overexpressed by various tumor entities, using
radiolabeled molecules for a combined diagnostic and therapeutic (theranostic) approach is …
radiolabeled molecules for a combined diagnostic and therapeutic (theranostic) approach is …
Gastrin-releasing peptide receptor agonists and antagonists for molecular imaging of breast and prostate cancer: from pre-clinical studies to translational perspectives
J Gorica, MS De Feo, L Filippi… - Expert Review of …, 2022 - Taylor & Francis
Introduction Prostate and breast cancer represent a leading cause of cancer-related death
worldwide with a dramatic social and demographic impact. Gastrin-releasing peptide …
worldwide with a dramatic social and demographic impact. Gastrin-releasing peptide …
An update of radiolabeled bombesin analogs for gastrin-releasing peptide receptor targeting
Z Yu, HJK Ananias, G Carlucci… - Current …, 2013 - ingentaconnect.com
Prostate cancer is a critical public health problem in USA and Europe. New non-invasive
imaging methods are urgently needed, due to the low accuracy and specificity of current …
imaging methods are urgently needed, due to the low accuracy and specificity of current …
Comparison of biological properties of [177Lu]Lu‐ProBOMB1 and [177Lu]Lu‐NeoBOMB1 for GRPR targeting
The gastrin‐releasing peptide receptor (GRPR) is overexpressed in prostate cancer and
other solid malignancies. Following up on our work on [68Ga] Ga‐ProBOMB1 that had better …
other solid malignancies. Following up on our work on [68Ga] Ga‐ProBOMB1 that had better …
Phase I Trial of [99mTc]Tc-maSSS-PEG2-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR …
V Chernov, A Rybina, R Zelchan, A Medvedeva… - Cancers, 2023 - mdpi.com
Simple Summary Prostate and breast cancers are the most common malignancies. Accurate
diagnosis and staging of diseases are important for the prognosis and determination of …
diagnosis and staging of diseases are important for the prognosis and determination of …
Prostate cancer theranostics targeting gastrin-releasing peptide receptors
Gastrin-releasing peptide receptors (GRPRs), part of the bombesin (BBN) family, are
aberrantly overexpressed in many cancers, including those of the breast, prostate, pancreas …
aberrantly overexpressed in many cancers, including those of the breast, prostate, pancreas …
Nuclear imaging of prostate cancer with gastrin-releasing-peptide-receptor targeted radiopharmaceuticals
HJK Ananias, IJ De Jong, RA Dierckx… - Current …, 2008 - ingentaconnect.com
Prostate cancer is one of the most common causes of cancer in men. Evaluating the different
stages of prostate cancer with conventional imaging techniques still proves difficult. Nuclear …
stages of prostate cancer with conventional imaging techniques still proves difficult. Nuclear …
A radiotracer for molecular imaging and therapy of gastrin-releasing peptide receptor–positive prostate cancer
The gastrin-releasing peptide receptor (GRPR) is overexpressed in many solid
malignancies, particularly in prostate and breast cancers, among others. We synthesized …
malignancies, particularly in prostate and breast cancers, among others. We synthesized …
Radiolabeled bombesin analogs
R Mansi, BA Nock, SU Dalm, MB Busstra… - Cancers, 2021 - mdpi.com
Simple Summary Recent medical advancements have strived for a personalized medicine
approach to patients, aimed at optimizing therapy outcomes with minimum toxicity. In this …
approach to patients, aimed at optimizing therapy outcomes with minimum toxicity. In this …
Lutetium-177 labeled bombesin peptides for radionuclide therapy
T Stott Reynolds, RP Bandari, Z Jiang… - Current …, 2016 - ingentaconnect.com
The rare-earth radionuclides that decay by beta particle (β-&) emission are considered to be
ideal in the context of targeted radiotherapy. The rare-earth isotopes exist primarily in the 3+ …
ideal in the context of targeted radiotherapy. The rare-earth isotopes exist primarily in the 3+ …