Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates

M Careaga, T Murai, MD Bauman - Biological psychiatry, 2017 - Elsevier
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …

Epidemiologic studies of exposure to prenatal infection and risk of schizophrenia and autism

AS Brown - Developmental neurobiology, 2012 - Wiley Online Library
In this review, we provide a synopsis of work on the epidemiologic evidence for prenatal
infection in the etiology of schizophrenia and autism. In birth cohort studies conducted by our …

Effects of prenatal infection on brain development and behavior: a review of findings from animal models

P Boksa - Brain, behavior, and immunity, 2010 - Elsevier
Epidemiological studies with human populations indicate associations between maternal
infection during pregnancy and increased risk in offspring for central nervous system (CNS) …

Prenatal stress, maternal immune dysregulation, and their association with autism spectrum disorders

DQ Beversdorf, HE Stevens, KL Jones - Current psychiatry reports, 2018 - Springer
Abstract Purpose of Review While genetic factors are a major etiological contributor to
autism spectrum disorder (ASD), evidence also supports a role for environmental factors …

Maternal infection and immune involvement in autism

PH Patterson - Trends in molecular medicine, 2011 - cell.com
Recent studies have highlighted a connection between infection during pregnancy and the
increased risk of autism in the offspring. Parallel studies of cerebral spinal fluid, blood and …

Maternal immune activation and autism spectrum disorder: interleukin-6 signaling as a key mechanistic pathway

EC Parker-Athill, J Tan - Neurosignals, 2011 - karger.com
An emerging area of research in autism spectrum disorder (ASD) is the role of prenatal
exposure to inflammatory mediators during critical developmental periods. Epidemiological …

[HTML][HTML] Gender-dependent effects of maternal immune activation on the behavior of mouse offspring

ICY Xuan, DR Hampson - PloS one, 2014 - journals.plos.org
Autism spectrum disorders are neurodevelopmental disorders characterized by two core
symptoms; impaired social interactions and communication, and ritualistic or repetitive …

Prenatal infection, maternal immune activation, and risk for schizophrenia

SE Canetta, AS Brown - Translational neuroscience, 2012 - Springer
A body of epidemiological literature has suggested an association between prenatal
infection, subsequent maternal immune activation (MIA), and later risk of schizophrenia …

Maternal immune activation and neuropsychiatric illness: a translational research perspective

AS Brown, U Meyer - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Epidemiologic studies, including prospective birth cohort investigations, have implicated
maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …

[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …