Non-coding RNAs regulating mitochondrial function in cardiovascular diseases

X Ao, W Ding, X Li, Q Xu, X Chen, X Zhou… - Journal of Molecular …, 2023 - Springer
Cardiovascular disease (CVD) is the leading cause of disease-related death worldwide and
a significant obstacle to improving patients' health and lives. Mitochondria are core …

[HTML][HTML] Mitochondrial noncoding RNA-regulatory network in cardiovascular disease

A Jusic, Y Devaux… - Basic research in …, 2020 - Springer
Mitochondrial function and integrity are vital for the maintenance of cellular homeostasis,
particularly in high-energy demanding cells. Cardiomyocytes have a large number of …

[HTML][HTML] ncRNAs: new players in mitochondrial health and disease?

M Gusic, H Prokisch - Frontiers in genetics, 2020 - frontiersin.org
The regulation of mitochondrial proteome is unique in that its components have origins in
both mitochondria and nucleus. With the development of OMICS technologies, emerging …

[HTML][HTML] Deciphering non-coding RNAs in cardiovascular health and disease

A Das, A Samidurai, FN Salloum - Frontiers in cardiovascular …, 2018 - frontiersin.org
After being long considered as “junk” in the human genome, non-coding RNAs (ncRNAs)
currently represent one of the newest frontiers in cardiovascular disease (CVD) since they …

Non‐coding RNA involvement in the pathogenesis of diabetic cardiomyopathy

W Zhang, W Xu, Y Feng, X Zhou - Journal of Cellular and …, 2019 - Wiley Online Library
In recent years, the incidence of diabetes has been increasing rapidly, which seriously
endangers human health. Diabetic cardiomyopathy, an important cardiovascular …

Noncoding RNAs in age-related cardiovascular diseases

A Jusic, PB Thomas, SB Wettinger, S Dogan… - Ageing Research …, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

[HTML][HTML] Mitochondrial MiRNA in cardiovascular function and disease

R Song, XQ Hu, L Zhang - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs functioning as crucial post-transcriptional
regulators of gene expression involved in cardiovascular development and health. Recently …

MitomiRs: new emerging microRNAs in mitochondrial dysfunction and cardiovascular disease

A Paramasivam, J Vijayashree Priyadharsini - Hypertension Research, 2020 - nature.com
Cardiovascular diseases (CVDs) are one of the leading causes of morbidity and mortality in
developed countries. CVDs are a group of disorders of the heart and blood vessels. They …

[HTML][HTML] Emerging functions of mitochondria-encoded noncoding RNAs

B Ren, MX Guan, T Zhou, X Cai, G Shan - Trends in Genetics, 2023 - cell.com
Mitochondria, organelles that harbor their own circular genomes, are critical for energy
production and homeostasis maintenance in eukaryotic cells. Recent studies discovered …

Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

C Bär, S Chatterjee, I Falcão Pires… - Cardiovascular …, 2020 - academic.oup.com
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …