More adolescents are coming out as transgender each year and are put on puberty blockers
to suppress natal puberty, which is then followed by cross-hormone treatment to achieve …

STUDY QUESTION Does testosterone use in females affect reproductive potential,
particularly with regard to the production of fertilizable gametes? SUMMARY ANSWER …

STUDY QUESTION Can mice serve as a translational model to investigate the reproductive
effects of testosterone (T) therapy commonly used by transgender men? SUMMARY …

STUDY QUESTION Can mice serve as a translational model to examine the reproductive
consequences of pubertal suppression with GnRH agonist (GnRHa) followed by …

Studies show that a subset of transgender men desire children; however, there is a paucity
of literature on the effect of gender-affirming testosterone therapy on reproductive function. In …

Some transmasculine individuals may be interested in pausing gender-affirming
testosterone therapy and carrying a pregnancy. The ovarian impact of taking and pausing …

Objective To establish if the cessation of testosterone (T) therapy reverses T-induced
acyclicity in a transgender mouse model that allows for well-defined T cessation timing …

Testosterone gender affirming hormone therapy (T-GAHT) is frequently used by transgender
and gender-diverse individuals assigned female at birth to establish masculinizing …

Abstract In the United States,~ 1.4 million individuals identify as transgender. Many
transgender adolescents experience gender dysphoria related to incongruence between …

Ovarian function is controlled by pituitary secretion of luteinizing hormone (LH) and follicle
stimulating hormone (FSH), which in turn are governed by gonadotropin releasing hormone …