Tempo-spectral multiplexing in flow cytometry with lifetime detection using QD-encoded polymer beads

D Kage, K Hoffmann, G Nifontova, V Krivenkov… - Scientific Reports, 2020 - nature.com
Semiconductor quantum dots (QDs) embedded into polymer microbeads are known to be
very attractive emitters for spectral multiplexing and colour encoding. Their luminescence …

Luminescence lifetime encoding in time-domain flow cytometry

D Kage, K Hoffmann, M Wittkamp, J Ameskamp… - Scientific reports, 2018 - nature.com
Time-resolved flow cytometry represents an alternative to commonly applied spectral or
intensity multiplexing in bioanalytics. At present, the vast majority of the reports on this topic …

Time-resolved microfluidic flow cytometer for decoding luminescence lifetimes in the microsecond region

Y Wang, N Sayyadi, X Zheng, TA Woods, RC Leif… - Lab on a Chip, 2020 - pubs.rsc.org
Time-resolved luminescence detection using long-lived probes with lifetimes in the
microsecond region have shown great potential in ultrasensitive and multiplexed …

Lifetime encoding in flow cytometry for bead-based sensing of biomolecular interaction

D Kage, K Hoffmann, H Borcherding, U Schedler… - Scientific reports, 2020 - nature.com
To demonstrate the potential of time-resolved flow cytometry (FCM) for bioanalysis, clinical
diagnostics, and optically encoded bead-based assays, we performed a proof-of-principle …

Luminescence encoding of polymer microbeads with organic dyes and semiconductor quantum dots during polymerization

L Scholtz, JG Eckert, T Elahi, F Lübkemann… - Scientific reports, 2022 - nature.com
Luminescence-encoded microbeads are important tools for many applications in the life and
material sciences that utilize luminescence detection as well as multiplexing and barcoding …

Multiplexed measurements by time resolved spectroscopy using colloidal CdSe/ZnS quantum dots

U Kaiser, D Jimenez de Aberasturi… - Applied Physics …, 2014 - pubs.aip.org
Multiplexed measurements of analytes in parallel is a topical demand in bioanalysis and
bioimaging. An interesting alternative to commonly performed spectral multiplexing is …

Micro-/nano-fluidic devices and in vivo fluorescence imaging based on quantum dots for cytologic diagnosis

M Luo, H Yukawa, Y Baba - Lab on a Chip, 2022 - pubs.rsc.org
Semiconductor quantum dots (QDs) possess attractive merits over traditional organic dyes,
such as tunable emission, narrow emission spectra and good resistance against optical …

Quantum dots in bioanalysis: a review of applications across various platforms for fluorescence spectroscopy and imaging

E Petryayeva, WR Algar, IL Medintz - Applied spectroscopy, 2013 - journals.sagepub.com
Semiconductor quantum dots (QDs) are brightly luminescent nanoparticles that have found
numerous applications in bioanalysis and bioimaging. In this review, we highlight recent …

Correlating semiconductor nanoparticle architecture and applicability for the controlled encoding of luminescent polymer microparticles

L Scholtz, JG Eckert, RT Graf, A Kunst, KD Wegner… - Scientific Reports, 2024 - nature.com
Luminophore stained micro-and nanobeads made from organic polymers like polystyrene
(PS) are broadly used in the life and material sciences as luminescent reporters, for bead …

Fluorescence lifetime multiplexing with nanocrystals and organic labels

M Grabolle, P Kapusta, T Nann, X Shu… - Analytical …, 2009 - ACS Publications
The potential of semiconducting nanocrystals or so-called quantum dots (QDs) for lifetime
multiplexing has not been investigated yet, despite the increasing use of QDs in (bio) …