Since the discovery of anticancer activity of cisplatin and other transition metal complexes, a
lot of compounds have been reported as containing ligand (s) bearing its (their) own …

The concept of multi-action octahedral platinum (IV) complexes is based on the rational
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …

Conspectus Platinum-based anticancer drugs are the mainstay of chemotherapy regimens
in clinic. Nevertheless, the efficacy of platinum drugs is badly affected by serious systemic …

Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …

One of the main problems in chemotherapy using platinum drugs as anticancer agents is the
resistance phenomenon. Synthesizing and evaluating valid alternative compounds is …

Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

It is one of the challenging works to deal with second major cause of death due to cancer
and to reduce the mortality rate caused by this. Researchers have been finding various …

Cisplatin, carboplatin and oxaliplatin are anticancer drugs, which are efficiently used in the
clinics all over the world. Besides a remarkable therapeutic efficacy in a series of solid …