Blood biomarkers for traumatic brain injury: a quantitative assessment of diagnostic and prognostic accuracy

ZS Gan, SC Stein, R Swanson, S Guan… - Frontiers in …, 2019 - frontiersin.org
Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …

Blood biomarkers in moderate-to-severe traumatic brain injury: potential utility of a multi-marker approach in characterizing outcome

AP Di Battista, JE Buonora, SG Rhind… - Frontiers in …, 2015 - frontiersin.org
Background Blood biomarkers are valuable tools for elucidating complex cellular and
molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of …

Blood-based biomarkers for traumatic brain injury: evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory …

FG Strathmann, S Schulte, K Goerl, DJ Petron - Clinical biochemistry, 2014 - Elsevier
Blood-based biomarkers for traumatic brain injury (TBI) have been investigated and
proposed for decades, yet the current clinical assessment of TBI is largely based on clinical …

[HTML][HTML] Exploring serum biomarkers for mild traumatic brain injury

L Papa, D Edwards, M Ramia - 2015 - europepmc.org
The diagnosis of traumatic brain injury (TBI) in the acute setting is based on neurological
examination and neuroimaging tools such as CT scanning and MRI. However, CT scanning …

The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury

ME Huibregtse, JJ Bazarian, SR Shultz… - … & Biobehavioral Reviews, 2021 - Elsevier
Abstract HUIBREGTSE, ME, Bazarian, JJ, Shultz, SR, and Kawata K. The biological
significance and clinical utility of emerging blood biomarkers for traumatic brain injury …

Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study

E Czeiter, K Amrein, BY Gravesteijn, F Lecky… - …, 2020 - thelancet.com
Background Serum biomarkers may inform and improve care in traumatic brain injury (TBI).
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …

Blood-based traumatic brain injury biomarkers–Clinical utilities and regulatory pathways in the United States, Europe and Canada

KK Wang, JC Munoz Pareja, S Mondello… - Expert review of …, 2021 - Taylor & Francis
Introduction Traumatic brain injury (TBI) is a major global health issue, resulting in
debilitating consequences to families, communities, and health-care systems. Prior research …

A blood-based biomarker panel to risk-stratify mild traumatic brain injury

R Sharma, A Rosenberg, ER Bennett, DT Laskowitz… - PloS one, 2017 - journals.plos.org
Mild traumatic brain injury (TBI) accounts for the vast majority of the nearly two million brain
injuries suffered in the United States each year. Mild TBI is commonly classified as …

Blood-based protein biomarkers for the management of traumatic brain injuries in adults presenting to emergency departments with mild brain injury: a living …

S Mondello, A Sorinola, E Czeiter, Z Vámos… - Journal of …, 2021 - liebertpub.com
Accurate diagnosis of traumatic brain injury (TBI) is critical to effective management and
intervention, but can be challenging in patients with mild TBI. A substantial number of …

An update on diagnostic and prognostic biomarkers for traumatic brain injury

KK Wang, Z Yang, T Zhu, Y Shi… - Expert review of …, 2018 - Taylor & Francis
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …