Background The progressive loss of cartilage matrix and the breakdown of articular cartilage
induced by inflammation play an essential role in osteoarthritis (OA) pathogenesis …

Rheumatoid arthritis (RA) is associated with systemic osteoporosis, which leads to severe
disability and low quality of life. Current therapies target osteoclasts to reduce bone …

Background Osteoarthritis (OA), a common chronic joint disease, is characterized by
cartilage degeneration and subchondral bone reconstruction. NF-κB signaling pathway …

Human and murine lymphocytes express dopamine (DA) D2‐like receptors including DRD2,
DRD3, and DRD4. However, their roles in rheumatoid arthritis (RA) are less clear. Here we …

Objective Emerging evidence has indicated that excessive reactive oxygen species (ROS)
have detrimental effects on osteoarthritis (OA). This study aimed to elucidate the effects of …

Systemic application of glucocorticoids is an essential anti-inflammatory and immune-
modulating therapy for severe inflammatory or autoimmunity conditions. However, its long …

Osteoarthritis (OA), a prevalent degenerative arthritis disease, principle characterized by the
destruction of cartilage and associated with the inflammatory response. Maltol, a product …

Preventing synovial fibroblast (SF) migration into the adjacent cartilage is a desirable
therapeutic target in rheumatoid arthritis (RA). As previous studies demonstrated that RASF …

Osteoarthritis (OA) is a common degenerative disease with few treatments. In traditional
Chinese medicine (TCM), Radix Angelicae biseratae (RAB) is commonly used to treat OA …

Objective Norepinephrine (NE) was measured in synovial fluid of trauma patients and
sympathetic nerve fibers were detected in healthy and osteoarthritic (OA) joint tissues …