Design, synthesis, molecular docking study, and α-glucosidase inhibitory evaluation of novel hydrazide–hydrazone derivatives of 3, 4-dihydroxyphenylacetic acid
A series of novel Schiff base derivatives (1–28) of 3, 4-dihydroxyphenylacetic acid were
synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high …
synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high …
Synthesis, in vitro α-glucosidase, anti-bacterial, anti-fungal activities and in silico molecular docking studies of benzohydrazide derivatives
In the present study, various alkyl substituted moieties were synthesized (1–15) and
characterized through various spectroscopic techniques such as 1 HNMR, 13 CNMR and …
characterized through various spectroscopic techniques such as 1 HNMR, 13 CNMR and …
Design, synthesis and evaluation of indole-based bisacylhydrazone derivatives as α-glucosidase inhibitors
CM Hu, YY Zheng, AT Lin, X Zhang, XZ Wu… - Journal of Molecular …, 2023 - Elsevier
A series of indole-based bisacylhydrazone derivatives 4a∼ 4v were synthesized and
assessed for their α-glucosidase activities. The results presented that all synthesized …
assessed for their α-glucosidase activities. The results presented that all synthesized …
Synthesis, biological evaluation and molecular docking studies of chromone hydrazone derivatives as α-glucosidase inhibitors
G Wang, M Chen, J Wang, Y Peng, L Li, ZZ Xie… - Bioorganic & Medicinal …, 2017 - Elsevier
A series of chromone hydrazone derivatives 4a–4p have been synthesized, characterized
by 1 H NMR and 13 C NMR and evaluated for their in vitro α-glucosidase inhibitory activity …
by 1 H NMR and 13 C NMR and evaluated for their in vitro α-glucosidase inhibitory activity …
Aryl-quinoline-4-carbonyl hydrazone bearing different 2-methoxyphenoxyacetamides as potent α-glucosidase inhibitors; molecular dynamics, kinetic and structure …
H Hamedifar, M Mirfattahi, M Khalili Ghomi… - Scientific Reports, 2024 - nature.com
Regarding the important role of α-glucosidase enzyme in the management of type 2
diabetes mellitus, the current study was established to design and synthesize aryl-quinoline …
diabetes mellitus, the current study was established to design and synthesize aryl-quinoline …
[HTML][HTML] Alpha-glucosidase inhibition analysis and in silico studies of new tetrahydroquinazolin-4 (1H)-one derivatives
A Tajmir-Riahi, MH Sayahi, MN Montazer… - Results in …, 2024 - Elsevier
In this work, a new series 3-phenylamine-2, 3-dihydroquinazolin-4 (1H)-one-phenoxy-
acetamid derivatives 7a-m was designed using by hybridization of effective …
acetamid derivatives 7a-m was designed using by hybridization of effective …
Design, synthesis, and molecular docking studies of diphenylquinoxaline-6-carbohydrazide hybrids as potent α-glucosidase inhibitors
K Pedrood, Z Rezaei, K Khavaninzadeh, B Larijani… - BMC chemistry, 2022 - Springer
A novel series of diphenylquinoxaline-6-carbohydrazide hybrids 7a–o were rationally
designed and synthesized as anti-diabetic agents. All synthesized compounds 7a–o were …
designed and synthesized as anti-diabetic agents. All synthesized compounds 7a–o were …
Synthesis, in vitro inhibitor screening, structure–activity relationship, and molecular dynamic simulation studies of novel thioquinoline derivatives as potent α …
RD Forozan, MK Ghomi, A Iraji, MN Montazer… - Scientific Reports, 2023 - nature.com
New series of thioquinoline structures bearing phenylacetamide 9a–p were designed,
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
synthesized and the structure of all derivatives was confirmed using different spectroscopic …
Novel polyhydroquinoline Schiff's base derivatives: synthesis, characterization, in vitro α-glucosidase inhibitory, and molecular docking studies
N Shahab, D Kong, M Ali, A Alam, N Ur Rehman… - Research on Chemical …, 2023 - Springer
Novel Schiff's base hydrazone derivatives (1–24) based on polyhydroquinoline (PHQ) were
synthesized in good to excellent yields via three step reactions. Compound 1 (starting …
synthesized in good to excellent yields via three step reactions. Compound 1 (starting …
[PDF][PDF] Haleh Hamedifar, Mahroo Mirfattahi 3, Minoo Khalili Ghomi 3, Homa Azizian 4, Aida Iraji 5, 6, Milad Noori 7, Ali Moazzam 3, Navid Dastyafteh 7, Ali …
MH Hajimiri, M Mahdavi - Scientific Reports, 2024 - researchgate.net
Regarding the important role of α‑glucosidase enzyme in the management of type 2
diabetes mellitus, the current study was established to design and synthesize aryl‑quinoline …
diabetes mellitus, the current study was established to design and synthesize aryl‑quinoline …
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