Mesenchymal stem cells-derived exosomes: a possible therapeutic strategy for osteoporosis

Y Li, D Jin, W Xie, L Wen, W Chen, J Xu… - Current stem cell …, 2018 - ingentaconnect.com
Osteoporosis is a common age-related disorder characterized by low bone mass and
deterioration in bone microarchitecture, leading to increased skeletal fragility and fracture …

[PDF][PDF] Exosomes derived from bone marrow mesenchymal stem cells improve osteoporosis through promoting osteoblast proliferation via MAPK pathway.

P Zhao, L Xiao, J Peng, YQ Qian… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Osteoporosis is the most common bone metabolic disease. Exosome exerts a
crucial role in the development of multiple diseases. The aim of the study was to investigate …

Potential effects of exosomes and their MicroRNA carrier on osteoporosis

QC Li, C Li, W Zhang, W Pi… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Osteoporosis is a common localized or systemic skeletal illness in the clinic, characterized
by bone production weakness and increased bone resorption, resulting in a reduction in …

Osteoporosis treatment by mesenchymal stromal/stem cells and their exosomes: Emphasis on signaling pathways and mechanisms

M Rudiansyah, AA El-Sehrawy, I Ahmad, EM Terefe… - Life Sciences, 2022 - Elsevier
Osteoporosis is the loss of bone density, which is one of the main problems in developed
and developing countries and is more common in the elderly. Because this disease is often …

[PDF][PDF] Bone marrow stem cells derived exosomes improve osteoporosis by promoting osteoblast proliferation and inhibiting cell apoptosis

Y Xie, JH Hu, H Wu, ZZ Huang… - Eur Rev Med …, 2019 - europeanreview.org
OBJECTIVE: The aim of this study was to investigate whether bone marrow stem cells
(MSCs) derived exosomes in rats could promote osteoblast proliferation and improve …

Bone marrow mesenchymal stem cell's exosomes as key nanoparticles in osteogenesis and bone regeneration: specific capacity based on cell type

MS Gholami Farashah, M Javadi, A Mohammadi… - Molecular Biology …, 2022 - Springer
Today, communities and their health systems are facing with several challenges associated
with the population ageing. Growing number of bone disorders is one of the most serious …

Human mesenchymal stem cell derived exosomes enhance cell‐free bone regeneration by altering their miRNAs profiles

M Zhai, Y Zhu, M Yang, C Mao - Advanced Science, 2020 - Wiley Online Library
Implantation of stem cells for tissue regeneration faces significant challenges such as
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …

Stem cell‐derived exosomes: a promising strategy for fracture healing

ZC Hao, J Lu, SZ Wang, H Wu, YT Zhang… - Cell …, 2017 - Wiley Online Library
Objectives To describe the biological characteristics of exosomes and to summarize the
current status of stem cell‐derived exosomes on fracture healing. Meanwhile, future …

Exosomes: a tool for bone tissue engineering

J Huber, MF Griffin, MT Longaker… - Tissue Engineering Part …, 2022 - liebertpub.com
Mesenchymal stem cells (MSCs) have been repeatedly shown to be a valuable source for
cell-based therapy in regenerative medicine, including bony tissue repair. However …

Immunoregulatory role of exosomes derived from differentiating mesenchymal stromal cells on inflammation and osteogenesis

F Wei, Z Li, R Crawford, Y Xiao… - Journal of tissue …, 2019 - Wiley Online Library
Bone marrow‐derived mesenchymal stem/stromal cells (BMSCs) can differentiate into bone‐
forming osteoblasts, playing a crucial role in bone regeneration. Exosomes are naturally cell …