Prenatal maternal stress alters depression-related symptoms in a strain-and sex-dependent manner in rodent offspring

M Enayati, B Mosaferi, JR Homberg, DM Diniz… - Life sciences, 2020 - Elsevier
Stress during pregnancy adversely affects foetal development and leads to later behavioural
outcomes in offspring. Preclinical studies have reported conflicting effects of prenatal stress …

Prenatal stress produces sex-specific changes in depression-like behavior in rats: implications for increased vulnerability in females

HM Sickmann, TS Arentzen, TB Dyrby… - … Origins of Health and …, 2015 - cambridge.org
Stress during rat gestation can elicit depression-like physiological and behavioral responses
in the offspring. However, human clinical depression is more prevalent among females than …

Prenatal psychological stress causes higher emotionality, depression-like behavior, and elevated activity in the hypothalamo-pituitary-adrenal axis

H Abe, N Hidaka, C Kawagoe, K Odagiri… - Neuroscience …, 2007 - Elsevier
In humans, stressful events during pregnancy may raise the risk of psychiatric disorders in
offspring, and studies with rodents have found that physical prenatal stress can cause …

Early-life stress reprograms stress-coping abilities in male and female juvenile rats

ME Pallarés, MC Monteleone, V Pastor… - Molecular …, 2021 - Springer
Prenatal stress (PS) is a major risk factor for the development of emotional disorders in
adulthood that may be mediated by an altered hypothalamic–pituitary–adrenal axis …

[HTML][HTML] Prenatal stress programs neuroendocrine stress responses and affective behaviors in second generation rats in a sex-dependent manner

NJ Grundwald, PJ Brunton - Psychoneuroendocrinology, 2015 - Elsevier
An adverse environment in early life is often associated with dysregulation of the
hypothalamo-pituitary-adrenal (HPA) axis and higher rates of mood disorders in adulthood …

Prenatal stress and neonatal rat brain development

DLA Van den Hove, HWM Steinbusch, A Scheepens… - Neuroscience, 2006 - Elsevier
Chronic or repeated stress during human fetal brain development has been associated with
various learning, behavioral, and/or mood disorders, including depression in later life. The …

[HTML][HTML] Vulnerability versus resilience to prenatal stress in male and female rats; implications from gene expression profiles in the hippocampus and frontal cortex

DLA Van den Hove, G Kenis, A Brass… - European …, 2013 - Elsevier
Adverse life events during pregnancy may impact upon the developing fetus, predisposing
prenatally stressed offspring to the development of psychopathology. In the present study …

[HTML][HTML] Mild prenatal stress causes emotional and brain structural modifications in rats of both sexes

C Soares-Cunha, B Coimbra, S Borges… - Frontiers in behavioral …, 2018 - frontiersin.org
Stress or high levels of glucocorticoids (GCs) during developmental periods is known to
induce persistent effects in the neuroendocrine circuits that control stress response, which …

Hippocampal NR3C1 DNA methylation can mediate part of preconception paternal stress effects in rat offspring

S Niknazar, A Nahavandi, AA Peyvandi… - Behavioural brain …, 2017 - Elsevier
Many studies have been shown that maternal stress during pregnancy and in early life
period influences offspring in the behavioral and molecular aspects in human and animal …

Effects of prenatal stress on anxiety‐and depressive‐like behaviours are sex‐specific in prepubertal rats

AM Iturra‐Mena, M Arriagada‐Solimano… - Journal of …, 2018 - Wiley Online Library
The foetal brain is highly susceptible to stress in late pregnancy, with lifelong effects of stress
on physiology and behaviour. The present study aimed to determine the physiological and …