Introduction Polyamines (putrescine, spermidine and spermine) are ubiquitous polycationic
metabolites in prokaryotic and eukaryotic cells. Their roles in the regulation of major …

In recent years the functions of polyamines (putrescine, spermidine, and spermine) have
been studied at the molecular level. Polyamines can modulate the functions of RNA, DNA …

The polyamines are low molecular mass aliphatic amines that can be synthesized by both
prokaryotic and eukaryotic cells. The most common are putrescine, spermidhe and spermine …

The term “polqamines” will be used in the following to designate putrescine(1,
4_butanediamine), spermidine [N-(3-aminopropyl)-I, 4-butane-diamine] and spermine[N, N' …

PerspectivesinBiologyandMedicine· Spring1979\421 metabolism of polyamines have been
uncovered in animals, plants, and microorganisms. Various polyamine biosynthetic …

The aliphatic polyamines, putrescine (1, 4diaminobutane), spermidine, and spermine, are
normal cell constituents that play an important role in cell proliferation and differentiation. At …

Despite the initial aversion to polyamine research which can be attributed to their peculiar
nomenclature and to the erroneous idea that polyamines are products of bacterial decay, it …

Francis Schuber, 1 Keelung Hong,** Nejat Düzgüne § , and Demetrios Papahadjopoulos
abstract: We have studied the effect of the polyamines (spermine, spermidine, and …

The polyamines, putrescine, spermidine and spermine, are simple aliphatic amines
exhibiting a wide range of biological activity [14]. The problem to be faced in elucidating their …

The naturally occurring polyamines, spermine [NH2 (CH2) 3NH (CH2) 4NH (CH2) 3NH2]
and spermidine [NH2 (CH2) 3NH (CH2) 4NH2], as well as the diamine putrescine [NH2 …