Results All groups showed similar Ki67-positive staining in RCC samples (p> 0.05). The
relative expression of HIF-1α and VEGF gradually increased in both group B and group C …

Laparoscopic surgery techniques have been increasingly preferred to classic laparotomy by
surgeons since 1987. However, this method may have some side effects on different …

The present study explored the inhibitory effect of hyperthermic CO2 pneumoperitoneum on
the proliferation and migration of colon cancer cells, and its mechanism. Colon cancer cell …

Background: Whether laparoscopy with CO 2 pneumoperitoneum affects the peritoneal
metastasis of gastric cancer is a pressing question. In light of the important impact change in …

Object: The authors studied the influence of CO 2 pneumoperitoneum on intracellular pH
and signal transduction arising from cancer cell multiplication in laparoscopic tumor …

Objectives We investigated the lethal effect of a hyperthermic CO 2 pneumoperitoneum on
gastric cancer cells. This could form the theoretical basis for further studies of the feasibility …

AIM: To observe the hepatic injury induced by carbon dioxide pneumoperitoneum in rats
and to explore its potential mechanism. METHODS: Thirty healthy male SD rats were …

Background: Peritoneal carcinomatosis (PC) arising from colorectal cancer is associated
with poor prognosis and few treatment options are currently available. Laparoscopic CO2 …

The effect of hyperthermic carbon dioxide (CO2) pneumoperitoneum in combination with 5-
fluorouracil (5-FU) on the proliferation and invasion of colon cancer was explored. Colon …

Methods Male Sprague-Dawley rats (250 g-350 g, from Shanghai Experimental A minal
Center) were anesthetized with 25 g/L sodium barbitone (1 μL/g). Abdomens were shaved …