Murray G, Harvey A. Circadian rhythms and sleep in bipolar disorder. Bipolar Disord 2010:
12: 459–472.© 2010 The Authors. Journal compilation© 2010 John Wiley & Sons A/S …

Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in
patients with bipolar disorder (BD). Irregularity of the sleep–wake rhythm, eveningness …

Abstract Background Bipolar Disorder is characterized by episodes running the full mood
spectrum, from mania to depression. Between mood episodes, residual symptoms remain …

Despite advances in the treatment of bipolar disorder, a significant proportion of patients
experience disabling symptoms between episodes, and relapse rates are high. These …

Abstract Purpose of Review We review recent evidence for circadian rhythm dysregulation in
bipolar spectrum disorders (BSDs). We examine evidence for endogenous abnormalities in …

Background: Rhythm disruption is a core feature of bipolar disorder and it has been
hypothesized that disturbances of the circadian timing system play a fundamental role in the …

Aim Symptoms of bipolar disorder (BD) include changes in mood, activity, energy, sleep,
and appetite. Since many of these processes are regulated by circadian function, circadian …

Despite a complex relationship between mood, sleep and rhythm, the impact of circadian
disruptions on bipolar disorder (BD) has not been clarified. The purpose of this systematic …

Purpose A role for circadian rhythm abnormalities in the pathogenesis of bipolar disorder
(BD) has been suggested. The present study assessed circadian preference, a subjective …

Bipolar disorders (BDs) are severe and common psychiatric disorders. BD pathogenesis,
clinical manifestations and relapses are associated with numerous circadian rhythm …