MicroRNAs as potential orchestrators of Alzheimer's disease-related pathologies: insights on current status and future possibilities

NZ Abuelezz, FE Nasr, MA AbdulKader… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and deleterious neurodegenerative disease,
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …

MicroRNA (miRNA)-mediated pathogenetic signaling in Alzheimer's disease (AD)

JM Hill, WJ Lukiw - Neurochemical research, 2016 - Springer
Alzheimer's disease (AD) is an expanding health and socioeconomic concern in
industrialized societies, and the leading cause of intellectual impairment in our aging …

MicroRNAs in Alzheimer's disease: diagnostic markers or therapeutic agents?

F Angelucci, K Cechova, M Valis, K Kuca… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding nucleic acids able to post-transcriptionally
regulate gene expression by binding to complementary sequences of target messenger …

The emerging role of microRNAs in Alzheimer's disease

GD Femminella, N Ferrara, G Rengo - Frontiers in physiology, 2015 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNA which have been shown to regulate gene
expression. The alteration ofmiRNAs expression has been associated with several …

Cerebrospinal fluid microRNAs as potential biomarkers in Alzheimer's disease

A Noor Eddin, K Hamsho, G Adi… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the leading form of dementia worldwide, but its early detection
and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous …

microRNA-based biomarkers in Alzheimer's disease (AD)

Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …

MicroRNAs in Alzheimer's disease: function and potential applications as diagnostic biomarkers

W Wei, ZY Wang, LN Ma, TT Zhang, Y Cao… - Frontiers in molecular …, 2020 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia. Although the incidence of
AD is high, the rates of diagnosis and treatment are relatively low. Moreover, effective means …

Insights into role of microRNA in Alzheimer's disease: from contemporary research to bedside perspective

M Bandakinda, A Mishra - International Journal of Biological …, 2023 - Elsevier
One of the most prevalent neurodegenerative disorders is Alzheimer's disease (AD). Despite
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …

The role of microRNAs in Alzheimer's disease and their therapeutic potentials

M Miya Shaik, IA Tamargo, MB Abubakar, MA Kamal… - Genes, 2018 - mdpi.com
MicroRNAs (miRNAs) are short, endogenous, non-coding RNAs that post-transcriptionally
regulate gene expression by base pairing with mRNA targets. Altered miRNA expression …

MicroRNA: implications for Alzheimer disease and other human CNS disorders

OC Maes, HM Chertkow, E Wang… - Current …, 2009 - ingentaconnect.com
Understanding complex diseases such as sporadic Alzheimer disease (AD) has been a
major challenge. Unlike the familial forms of AD, the genetic and environmental risks factors …