Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats
RK Bachtell, DW Self - Psychopharmacology, 2009 - Springer
Rationale Dopamine (DA) receptor stimulation in the nucleus accumbens (NAc) plays an
important role in regulating cocaine-seeking behavior. Adenosine receptors antagonize the …
important role in regulating cocaine-seeking behavior. Adenosine receptors antagonize the …
[HTML][HTML] Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats
CE O'neill, ML LeTendre, RK Bachtell - Neuropsychopharmacology, 2012 - nature.com
Repeated cocaine administration enhances dopamine D 2 receptor sensitivity in the
mesolimbic dopamine system, which contributes to drug relapse. Adenosine A 2A receptors …
mesolimbic dopamine system, which contributes to drug relapse. Adenosine A 2A receptors …
Persistent reduction of cocaine seeking by pharmacological manipulation of adenosine A1 and A2A receptors during extinction training in rats
Rationale Adenosine receptor stimulation and blockade have been shown to modulate a
variety of cocaine-related behaviors. Objectives These studies identify the direct effects of …
variety of cocaine-related behaviors. Objectives These studies identify the direct effects of …
Effects of adenosine A2A receptor antagonists on cocaine-induced locomotion and cocaine seeking
NS Haynes, CE O'Neill, BD Hobson, RK Bachtell - Psychopharmacology, 2019 - Springer
Rationale and objectives Adenosine signaling through adenosine A 2A receptors (A 2A Rs)
is known to influence cocaine-induced behaviors. These studies sought to elucidate how …
is known to influence cocaine-induced behaviors. These studies sought to elucidate how …
On the role of adenosine (A)2A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats
K Wydra, K Gołembiowska, A Suder, K Kamińska… - …, 2015 - Springer
Rationale Several studies have suggested the inhibitory control of adenosine (A) 2A
receptor stimulation in cocaine-induced behavioral actions. Objectives A combination of …
receptor stimulation in cocaine-induced behavioral actions. Objectives A combination of …
[HTML][HTML] Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats
K Wydra, A Suder, M Frankowska… - …, 2018 - Springer
Rationale and objectives Many studies indicated that adenosine via its A 2A receptors
influences the behavioral effects of cocaine by modulating dopamine neurotransmission …
influences the behavioral effects of cocaine by modulating dopamine neurotransmission …
[HTML][HTML] On the role of A2A and D2 receptors in control of cocaine and food-seeking behaviors in rats
K Wydra, A Suder, DO Borroto-Escuela, M Filip… - …, 2015 - Springer
Recent studies indicate that adenosine may influence dopamine neurotransmission via A 2A
receptors which antagonistically interact with D 2 receptor-mediated signaling in the brain …
receptors which antagonistically interact with D 2 receptor-mediated signaling in the brain …
Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats
SE Doyle, FJ Breslin, JM Rieger, A Beauglehole… - Pharmacology …, 2012 - Elsevier
Adenosine is an important neuromodulator, known to interact with both dopaminergic and
glutamatergic systems to influence psychostimulant action. In the present study, we …
glutamatergic systems to influence psychostimulant action. In the present study, we …
The adenosine receptor antagonist CGS15943 reinstates cocaine-seeking behavior and maintains self-administration in baboons
EM Weerts, RR Griffiths - Psychopharmacology, 2003 - Springer
Rationale Caffeine and the adenosine A 1 and A 2A receptor antagonist CGS15943
produce many behavioral effects that are similar to those produced by classic stimulant …
produce many behavioral effects that are similar to those produced by classic stimulant …
Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in …
BD Hobson, KE Merritt, RK Bachtell - Neuropharmacology, 2012 - Elsevier
Adenosine receptors co-localize with dopamine receptors on medium spiny nucleus
accumbens (NAc) neurons where they antagonize dopamine receptor activity. It remains …
accumbens (NAc) neurons where they antagonize dopamine receptor activity. It remains …