Neuroglia in neurodegeneration
MT Heneka, JJ Rodríguez, A Verkhratsky - Brain research reviews, 2010 - Elsevier
Neuroglial cells are fundamental for control of brain homeostasis and they represent the
intrinsic brain defence system. All forms in neuropathology therefore inevitably involve glia …
intrinsic brain defence system. All forms in neuropathology therefore inevitably involve glia …
Neuroglial roots of neurodegenerative diseases?
JJ Rodríguez, A Verkhratsky - Molecular neurobiology, 2011 - Springer
Neuroglia is critically important for controlling the brain homeostasis and for mounting the
brain defence against pathological insults. Here, we overview recent data about the role of …
brain defence against pathological insults. Here, we overview recent data about the role of …
[HTML][HTML] Glia: the fulcrum of brain diseases
C Giaume, F Kirchhoff, C Matute… - Cell Death & …, 2007 - nature.com
Neuroglia represented by astrocytes, oligodendrocytes and microglial cells provide for
numerous vital functions. Glial cells shape the micro-architecture of the brain matter; they are …
numerous vital functions. Glial cells shape the micro-architecture of the brain matter; they are …
Glial cells and integrity of the nervous system
R von Bernhardi, J Eugenín-von Bernhardi… - Glial Cells in Health and …, 2016 - Springer
Today, there is enormous progress in understanding the function of glial cells, including
astroglia, oligodendroglia, Schwann cells, and microglia. Around 150 years ago, glia were …
astroglia, oligodendroglia, Schwann cells, and microglia. Around 150 years ago, glia were …
[HTML][HTML] Regional brain susceptibility to neurodegeneration: what is the role of glial cells?
AB Cragnolini, G Lampitella, A Virtuoso… - Neural Regeneration …, 2020 - journals.lww.com
The main pathological feature of the neurodegenerative diseases is represented by
neuronal death that represents the final step of a cascade of adverse/hostile events. Early in …
neuronal death that represents the final step of a cascade of adverse/hostile events. Early in …
[HTML][HTML] Microglia and astrocyte involvement in neurodegeneration and brain cancer
AA Vandenbark, H Offner, S Matejuk… - Journal of …, 2021 - Springer
The brain is unique and the most complex organ of the body, containing neurons and
several types of glial cells of different origins and properties that protect and ensure normal …
several types of glial cells of different origins and properties that protect and ensure normal …
Glia in the pathogenesis of neurodegenerative diseases
Exclusively neuron-centric approaches to neuropathological mechanisms have not resulted
in major new breakthroughs in the prevention and therapy of neurodegenerative diseases …
in major new breakthroughs in the prevention and therapy of neurodegenerative diseases …
Emerging role of neuron‐glia in neurological disorders: at a glance
Based on the diverse physiological influence, the impact of glial cells has become much
more evident on neurological illnesses, resulting in the origins of many diseases appearing …
more evident on neurological illnesses, resulting in the origins of many diseases appearing …
Translational potential of astrocytes in brain disorders
Fundamentally, all brain disorders can be broadly defined as the homeostatic failure of this
organ. As the brain is composed of many different cells types, including but not limited to …
organ. As the brain is composed of many different cells types, including but not limited to …
[HTML][HTML] Astrogliosis as a therapeutic target for neurodegenerative diseases
Chronic neurodegenerative diseases represent major unmet needs for therapeutic
interventions. Recently, the neurocentric view of brain function and disease has been …
interventions. Recently, the neurocentric view of brain function and disease has been …