Shared genetic influences on adolescent body mass index and brain structure: a voxel-based morphometry study in twins

JT Kennedy, SV Astafiev, S Golosheykin, O Korucuoglu… - Neuroimage, 2019 - Elsevier
Background Previous research has demonstrated significant relationships between obesity
and brain structure. Both phenotypes are heritable, but it is not known whether they are …

The obese brain as a heritable phenotype: a combined morphometry and twin study

CM Weise, P Piaggi, M Reinhardt, K Chen… - International journal of …, 2017 - nature.com
Background: Body weight and adiposity are heritable traits. To date, it remains unknown
whether obesity-associated brain structural alterations are under a similar level of genetic …

Brain structural differences in monozygotic twins discordant for body mass index

CM Weise, T Bachmann, B Pleger - Neuroimage, 2019 - Elsevier
Background Substantial efforts have been made to investigate the neurobiological
underpinnings of human obesity with a number of studies indicating a profound influence of …

Identification of pleiotropic genetic effects on obesity and brain anatomy

JE Curran, DR McKay, AM Winkler, RL Olvera… - Human …, 2013 - karger.com
Abstract Background/Aims: Obesity is a major contributor to the global burden of chronic
disease and disability, though current knowledge of causal biologic underpinnings is …

Familial obesity risk and current excess weight influence brain structure in adolescents

G Thapaliya, L Chen, E Jansen, KR Smith, JR Sadler… - …, 2021 - Wiley Online Library
Objective Obesity risk transmits from parents to children. Underlying neural mechanisms
were investigated in this study by evaluating influences of familial obesity risk defined by …

Neurobehavioral correlates of obesity are largely heritable

U Vainik, TE Baker, M Dadar… - Proceedings of the …, 2018 - National Acad Sciences
Recent molecular genetic studies have shown that the majority of genes associated with
obesity are expressed in the central nervous system. Obesity has also been associated with …

Triangulating causality between childhood obesity and neurobehavior: Behavioral genetic and longitudinal evidence

LK Kulisch, K Arumäe, DA Briley… - Developmental …, 2023 - Wiley Online Library
Childhood obesity is a serious health concern that is not yet fully understood. Previous
research has linked obesity with neurobehavioral factors such as behavior, cognition, and …

Obesity is associated with decreased gray matter volume in children: a longitudinal study

F Jiang, G Li, W Ji, Y Zhang, F Wu, Y Hu… - Cerebral …, 2023 - academic.oup.com
Childhood obesity has become a global health problem. Previous studies showed that
childhood obesity is associated with brain structural differences relative to controls …

[HTML][HTML] Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters

A Tüngler, S Van der Auwera, K Wittfeld, S Frenzel… - Scientific reports, 2021 - nature.com
Evidence from previous studies suggests that elevated body mass index (BMI) and genetic
risk for obesity is associated with reduced brain volume, particularly in areas of reward …

Genetic and environmental influences on cortical thickness among 14-year-old twins

Y Yang, AA Joshi, SH Joshi, LA Baker, KL Narr… - …, 2012 - journals.lww.com
The overall volume of the brain has been found to be under relatively strong genetic control,
but the relative strength of genetic and environmental factors on between-person variations …