Shared genetic influences on adolescent body mass index and brain structure: a voxel-based morphometry study in twins
JT Kennedy, SV Astafiev, S Golosheykin, O Korucuoglu… - Neuroimage, 2019 - Elsevier
Background Previous research has demonstrated significant relationships between obesity
and brain structure. Both phenotypes are heritable, but it is not known whether they are …
and brain structure. Both phenotypes are heritable, but it is not known whether they are …
The obese brain as a heritable phenotype: a combined morphometry and twin study
Background: Body weight and adiposity are heritable traits. To date, it remains unknown
whether obesity-associated brain structural alterations are under a similar level of genetic …
whether obesity-associated brain structural alterations are under a similar level of genetic …
Brain structural differences in monozygotic twins discordant for body mass index
CM Weise, T Bachmann, B Pleger - Neuroimage, 2019 - Elsevier
Background Substantial efforts have been made to investigate the neurobiological
underpinnings of human obesity with a number of studies indicating a profound influence of …
underpinnings of human obesity with a number of studies indicating a profound influence of …
Identification of pleiotropic genetic effects on obesity and brain anatomy
JE Curran, DR McKay, AM Winkler, RL Olvera… - Human …, 2013 - karger.com
Abstract Background/Aims: Obesity is a major contributor to the global burden of chronic
disease and disability, though current knowledge of causal biologic underpinnings is …
disease and disability, though current knowledge of causal biologic underpinnings is …
Familial obesity risk and current excess weight influence brain structure in adolescents
Objective Obesity risk transmits from parents to children. Underlying neural mechanisms
were investigated in this study by evaluating influences of familial obesity risk defined by …
were investigated in this study by evaluating influences of familial obesity risk defined by …
Neurobehavioral correlates of obesity are largely heritable
Recent molecular genetic studies have shown that the majority of genes associated with
obesity are expressed in the central nervous system. Obesity has also been associated with …
obesity are expressed in the central nervous system. Obesity has also been associated with …
Triangulating causality between childhood obesity and neurobehavior: Behavioral genetic and longitudinal evidence
Childhood obesity is a serious health concern that is not yet fully understood. Previous
research has linked obesity with neurobehavioral factors such as behavior, cognition, and …
research has linked obesity with neurobehavioral factors such as behavior, cognition, and …
Obesity is associated with decreased gray matter volume in children: a longitudinal study
F Jiang, G Li, W Ji, Y Zhang, F Wu, Y Hu… - Cerebral …, 2023 - academic.oup.com
Childhood obesity has become a global health problem. Previous studies showed that
childhood obesity is associated with brain structural differences relative to controls …
childhood obesity is associated with brain structural differences relative to controls …
[HTML][HTML] Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters
A Tüngler, S Van der Auwera, K Wittfeld, S Frenzel… - Scientific reports, 2021 - nature.com
Evidence from previous studies suggests that elevated body mass index (BMI) and genetic
risk for obesity is associated with reduced brain volume, particularly in areas of reward …
risk for obesity is associated with reduced brain volume, particularly in areas of reward …
Genetic and environmental influences on cortical thickness among 14-year-old twins
The overall volume of the brain has been found to be under relatively strong genetic control,
but the relative strength of genetic and environmental factors on between-person variations …
but the relative strength of genetic and environmental factors on between-person variations …