Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse inhibition of the acoustic startle response in the rat

M Koch, M Kungel, H Herbert - Experimental Brain Research, 1993 - Springer
The amplitude of the acoustic startle response (ASR) is markedly reduced when the startle
eliciting pulse is preceded by a weak, non-startling stimulus at an appropriate lead time …

Quinolinic acid lesions of the ventral striatum reduce sensorimotor gating of acoustic startle in rats

MH Kodsi, NR Swerdlow - Brain research, 1994 - Elsevier
The startle reflex is inhibited when the startling stimulus is preceded 30–500 ms by a weak
noise or 'prepulse'. While the primary startle circuit is organized at or below the pons, the …

Midbrain pathways for prepulse inhibition and startle activation in rat

JS Yeomans, J Lee, MH Yeomans, S Steidl, L Li - Neuroscience, 2006 - Elsevier
The midbrain is essential for prepulse inhibition (PPI) of the startle reflex, but the exact
neural circuits for PPI are not yet determined. Electrical stimulation of the superior colliculus …

Brain stem circuits mediating prepulse inhibition of the startle reflex

M Fendt, L Li, JS Yeomans - Psychopharmacology, 2001 - Springer
Rationale: Prepulse inhibition (PPI) of the startle reflex occurs when brief, non-startling
tactile, acoustic or visual stimuli are presented 20–500 ms before the startling stimulus …

Prepulse inhibition of acoustic startle in rats after lesions of the pedunculopontine tegmental nucleus.

NR Swerdlow, MA Geyer - Behavioral neuroscience, 1993 - psycnet.apa.org
Prepulse inhibition (PPI) of startle is impaired in schizophrenics, which suggests they have
disturbances in circuitry that controls PPI. How activity in forebrain circuitry is communicated …

Regulation of prepulse inhibition by ventral pallidal projections

MH Kodsi, NR Swerdlow - Brain research bulletin, 1997 - Elsevier
The acoustic startle reflex is inhibited by the presentation of a weak auditory prestimulus 30–
500 ms prior to the startling stimulus. Previous studies have demonstrated that prepulse …

Prepulse inhibition in the rat is regulated by ventral and caudodorsal striato-pallidal circuitry.

MH Kodsi, NR Swerdlow - Behavioral neuroscience, 1995 - psycnet.apa.org
It has been shown that the acoustic startle reflex is inhibited by weak auditory prepulses
presented 30–500 ms prior to the startling stimulus and that this prepulse inhibition (PPI) is …

Cholinergic modulation of the acoustic startle response in the caudal pontine reticular nucleus of the rat

M Fendt, M Koch - European journal of pharmacology, 1999 - Elsevier
The startle response is a useful behavioural model to assess drug effects on sensorimotor
information processing in the mammalian central nervous system. Prepulse inhibition of the …

Ventral pallidal GABA-A receptors regulate prepulse inhibition of acoustic startle

MH Kodsi, NR Swerdlow - Brain research, 1995 - Elsevier
Prepulse inhibition (PPI) of the acoustic startle reflex occurs when a weak auditory stimulus
is presented 30–500 ms before the startling stimulus. Previous studies have shown that PPF …

The ventral pallidum mediates disruption of prepulse inhibition of the acoustic startle response induced by dopamine agonists, but not by NMDA antagonists

BD Kretschmer, M Koch - Brain research, 1998 - Elsevier
Prepulse inhibition (PPI) of the acoustic startle response is observed when the startling
noise pulse is preceded by a weak, non-startling stimulus. PPI has been considered as a …