Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

Secreted frizzled related protein 1 (SFRP1) is an antagonist of the transmembrane frizzled
receptor, a component of the Wnt signaling pathway, and has been suggested to be a …

Expression of Secreted frizzled related protein 1 (SFRP1), a recently identified tumor
suppressor gene encoding a WNT signaling antagonist, has been found to be frequently …

Disruption of the Wnt pathway is thought to be crucial in the development of human cancer.
Pathway inhibitory members of the secreted frizzled-related protein (SFRP) family were …

The role of secreted frizzled-related protein (SFRP) genes in gastric cancer remains largely
unknown. We determined the frequency and functional significance of SFRPs …

Abstract Secreted frizzled‐related protein‐5 (sFRP‐5) has been identified as 1 of the
secreted antagonists that bind Wnt protein. However, the functional significance of sFRP‐5 …

Background Hepatocellular carcinoma (HCC) is one of the most common cancers in the
world. SFRP1 (the secreted frizzled-related protein 1), a putative tumor suppressor gene …

BACKGROUND. The secreted frizzled‐related protein 1 gene (SFRP1) encodes a Wnt/β‐
catenin signaling antagonist and frequently is inactivated by promoter methylation in many …

Secreted frizzled-related protein 1 (SFRP1) is a candidate tumor suppressor gene located at
8p11. 2 and antagonizes the Wnt signaling pathway. Epigenetic inactivation of SFRP1 by …

The secreted Frizzled-related proteins (sFRP) are modulators of the Wnt signaling pathway,
which is involved in embryonic development and tumor progression. The functions of sFRP2 …