Background: This article outlines therapeutic mechanisms of hyperbaric oxygen therapy and
reviews data on its efficacy for clinical problems seen by plastic and reconstructive …

Nonhealing wounds are a major health problem worldwide. Managing difficult wounds often
involves prolonged hospitalizations, numerous surgical interventions, and medical wound …

The most important effects of hyperbaric oxygen (HBO), for the surgeon, are the stimulation
of leukocyte microbial killing, the enhancement of fibroblast replication, and increased …

Background: Adjunctive hyperbaric oxygen therapy is a safe and effective modality with
which to increase tissue oxygenation and aid in healing of difficult wounds. The majority of …

Hyperbaric oxygen has been advocated, both as an adjunctive or primary form of treatment,
for a variety of disorders, including gas gangrene, osteoradionecrosis, and carbon monoxide …

Background: Among advanced therapeutic interventions for wounds, hyperbaric oxygen
therapy (HBOT) has the unique ability to ameliorate tissue hypoxia, reduce pathologic …

Hyperbaric oxygen therapy (HBOT) serves as “primary” or “adjunctive” therapy in a wide
range of pathologies. It is considered the mainstay of management for potentially life …

Hyperbaric oxygen therapy (HBOT) is the use of 100% oxygen at pressures greater than
atmospheric pressure. Today several approved applications and indications exist for HBOT …

This article is a systematic review evaluating published clinical evidence of the efficacy of
hyperbaric oxygen therapy (HBOT) for wound healing and limb salvage. The data source is …

Significance: Tissue grafts and flaps are used to reconstruct wounds from trauma, chronic
disease, tumor extirpation, burns, and infection. Despite careful surgical planning and …