Sensing and transduction of nutritional and chemical signals in filamentous fungi: Impact on cell development and secondary metabolites biosynthesis

JF Martín, MA Van Den Berg, EVL Van Themaat… - Biotechnology …, 2019 - Elsevier
Filamentous fungi respond to hundreds of nutritional, chemical and environmental signals
that affect expression of primary metabolism and biosynthesis of secondary metabolites …

G-protein-coupled receptors in fungi

MMH El-Defrawy, AEL Hesham - Fungal biotechnology and …, 2020 - Springer
G-protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in
fungi. These receptors have an important role in the transduction of extracellular signals into …

G‐protein coupled receptor‐mediated nutrient sensing and developmental control in Aspergillus nidulans

NA Brown, TF Dos Reis, LNA Ries… - Molecular …, 2015 - Wiley Online Library
Nutrient sensing and utilisation are fundamental for all life forms. As heterotrophs, fungi have
evolved a diverse range of mechanisms for sensing and taking up various nutrients. Despite …

Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi

C Xue, YP Hsueh, J Heitman - FEMS microbiology reviews, 2008 - academic.oup.com
G protein-coupled receptors (GPCRs) represent the largest family of transmembrane
receptors and are responsible for transducing extracellular signals into intracellular …

[HTML][HTML] Identification of Metabolic Pathways Influenced by the G-Protein Coupled Receptors GprB and GprD in Aspergillus nidulans

WR de Souza, ER Morais, NG Krohn, M Savoldi… - PLoS …, 2013 - journals.plos.org
Heterotrimeric G-protein-mediated signaling pathways play a pivotal role in transmembrane
signaling in eukaryotes. Our main aim was to identify signaling pathways regulated by A …

Global survey of canonical Aspergillus flavus G protein-coupled receptors

KJ Affeldt, J Carrig, M Amare, NP Keller - MBio, 2014 - Am Soc Microbiol
ABSTRACT G protein-coupled receptors (GPCRs) are transmembrane receptors that relay
signals from the external environment inside the cell, allowing an organism to adapt to its …

[HTML][HTML] GPCR-mediated glucose sensing system regulates light-dependent fungal development and mycotoxin production

TF Dos Reis, L Mellado, JM Lohmar, LP Silva… - PLoS …, 2019 - journals.plos.org
Microorganisms sense environmental fluctuations in nutrients and light, coordinating their
growth and development accordingly. Despite their critical roles in fungi, only a few G …

Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans

Y Jae-Hyuk - Journal of Microbiology, 2006 - koreascience.kr
Heterotrimeric G proteins (G proteins) are conserved in all eukaryotes and are crucial
components sensing and relaying external cues into the cells to elicit appropriate …

Heterotrimeric G protein signaling in filamentous fungi

L Li, SJ Wright, S Krystofova, G Park… - Annu. Rev …, 2007 - annualreviews.org
Filamentous fungi are multicellular eukaryotic organisms known for nutrient recycling as well
as for antibiotic and food production. This group of organisms also contains the most …

Nutrient sensing G protein-coupled receptors: interesting targets for antifungals?

PV Dijck - Sabouraudia, 2009 - academic.oup.com
G protein-coupled receptors (GPCRs) are important targets for various drugs that are on the
market. An important area in which we urgently need novel drug targets is the field of …