The embolic MCA occlusion model in rats is used for recanalisation studies in acute stroke.
In addition to the determination of lesion size, the assessment of functional outcome may …

Stroke is a major cause of death and disability worldwide. However, treatment options to
date are very limited. To meet the need for validating the novel therapeutic approaches and …

We developed a new model of embolic cerebral ischemia in the rat which provides a
reproducible and predictable infarct volume within the territory supplied by the middle …

PURPOSE: Current rabbit stroke models often depend on symptoms as endpoints for
embolization and produce wide variation in location, size, and severity of strokes. In a further …

A number of models of focal ischemia have been created to mimic acute middle cerebral
artery (MCA) occlusion. In the present series of experiments, we report our observations on …

The present study describes a method for improving the precision and accuracy of clot
placement within the middle cerebral artery (MCA) of rats, utilizing a micro-catheter and …

We have used magnetic resonance imaging (MRI) techniques to characterise a rat model of
thromboembolic stroke. The consequences of acute perfusion deficit associated with a …

Background: Neurological outcomes and behavioral assessments are widely used in animal
models of stroke, but assessments in rabbit models are not fully validated. The wryneck …

This study characterizes a new model of thromboembolic stroke of the middle cerebral artery
in C57 black/6J mice, thus offering an opportunity to use the model for studying ischemic …

Ischemic stroke accounts for over 80% in total human stroke which mostly affect middle
cerebral artery (MCA) territory. Embolic stroke models induced by injection of homologous …