Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection
M Van der Valk, EH Gisolf, P Reiss, F Wit, A Japour… - Aids, 2001 - journals.lww.com
Background Changes in body fat distribution are an adverse effect of therapy with HIV
protease inhibitors (PI). It has been suggested that nucleoside analogue reverse …
protease inhibitors (PI). It has been suggested that nucleoside analogue reverse …
Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction
R de Waal, K Cohen, G Maartens - PloS one, 2013 - journals.plos.org
Background Lipoatrophy and/or central fat gain are observed frequently in patients on
antiretroviral therapy (ART). Both are assumed to be antiretroviral adverse drug reactions …
antiretroviral therapy (ART). Both are assumed to be antiretroviral adverse drug reactions …
Risk of lipodystrophy in HIV-1-infected patients treated with protease inhibitors: a prospective cohort study
E Martinez, A Mocroft, MA García-Viejo… - The Lancet, 2001 - thelancet.com
Background Risk factors for lipodystrophy in patients infected with HIV-1 treated with highly
active antiretroviral therapy (HAART) containing HIV-1 protease inhibitors are poorly …
active antiretroviral therapy (HAART) containing HIV-1 protease inhibitors are poorly …
A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
T Saint-Marc, M Partisani, I Poizot-Martin, F Bruno… - Aids, 1999 - journals.lww.com
Objective: To compare body composition, body fat distribution and insulin secretion in
patients taking nucleoside reverse transcriptase inhibitor (NRTI) therapy. Design and setting …
patients taking nucleoside reverse transcriptase inhibitor (NRTI) therapy. Design and setting …
Metabolic complications associated with antiretroviral therapy
RG Jain, ES Furfine, L Pedneault, AJ White… - Antiviral research, 2001 - Elsevier
Mortality rates in the HIV-infected patient population have decreased with the advent of
highly active antiretroviral therapy (HAART) for the treatment of AIDS. Due to the chronic …
highly active antiretroviral therapy (HAART) for the treatment of AIDS. Due to the chronic …
HIV and antiretroviral therapy-related fat alterations
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection
Background Progressive subcutaneous fat wasting, fat accumulation, dyslipidaemia and
insulin resistance in HIV-infected patients on antiretroviral therapy has been attributed to the …
insulin resistance in HIV-infected patients on antiretroviral therapy has been attributed to the …
The effects of discontinuing stavudine therapy on clinical and metabolic abnormalities in patients suffering from lipodystrophy
T Saint-Marc, JL Touraine - Aids, 1999 - journals.lww.com
A syndrome combining peripheral fat wasting (affecting facial fat pads, arms and legs),
insulin resistance and hyperlipidaemia has been identified in HIV-infected patients treated …
insulin resistance and hyperlipidaemia has been identified in HIV-infected patients treated …
Long‐term complications of antiretroviral therapy: lipoatrophy
L Waters, M Nelson - International Journal of Clinical Practice, 2007 - Wiley Online Library
The effective use of potent antiretroviral therapy has dramatically improved the life
expectancy for HIV‐infected individuals. Long‐term complications of both HIV‐infection and …
expectancy for HIV‐infected individuals. Long‐term complications of both HIV‐infection and …
Antiretroviral-therapy-associated lipoatrophy: current status and future directions
D Nolan, S Mallal - Sexual Health, 2005 - CSIRO Publishing
Lipoatrophy is perhaps the most visibly recognisable component of antiretroviral-therapy-
associated lipodystrophy due to the rarity of this form of body composition change in the …
associated lipodystrophy due to the rarity of this form of body composition change in the …