Giant prolactinomas: the therapeutic approach

AB Moraes, C Marques dos Santos Silva… - Clinical …, 2013 - Wiley Online Library
Background Giant prolactinomas are an unusual subset of macroprolactinomas and are
more commonly found in men. The goal of this review is to propose a giant prolactinoma …

Giant prolactinoma and effectiveness of medical management

SV Acharya, RA Gopal, PS Menon, TR Bandgar… - Endocrine Practice, 2010 - Elsevier
Objective To review our experience with long-term cabergoline and bromocriptine therapy in
the treatment of giant prolactinomas. Methods Patients with giant prolactinomas diagnosed …

Giant prolactinomas: are they really different from ordinary macroprolactinomas?

E Espinosa, E Sosa, V Mendoza, C Ramírez, V Melgar… - Endocrine, 2016 - Springer
Giant prolactinomas (gPRLomas) are rare tumors of the lactotroph defined by an unusually
large size (> 4 cm) and serum PRL levels> 1000 ng/mL. The purpose of this study is to …

Giant prolactinomas in men: efficacy of cabergoline treatment

SM Corsello, G Ubertini, M Altomare… - Clinical …, 2003 - Wiley Online Library
Summary objective The term 'giant prolactinoma'can be used for tumours larger than 4 cm in
diameter and/or with massive extrasellar extension. Cabergoline (CAB), a long‐lasting …

Management and outcomes of giant prolactinoma: a series of 71 patients

O ksana Hamidi, J Van Gompel, L Gruber, NE Kittah… - Endocrine Practice, 2019 - Elsevier
Objective: To describe outcomes of patients with giant prolactinoma (≥ 4 cm) and identify
predictors of therapeutic response. Methods: In this retrospective study, complete …

Long-term Follow-up of 84 Patients With Giant Prolactinomas—A Swedish Nationwide Study

C Himonakos, P Burman, H Borg… - The Journal of …, 2023 - academic.oup.com
Purpose To describe the clinical presentation and treatment outcomes in a nationwide
cohort of patients with giant prolactinomas. Methods Register-based study of patients with …

Effectiveness of long-term cabergoline treatment for giant prolactinoma: study of 12 men

I Shimon, C Benbassat, M Hadani - European Journal of …, 2007 - academic.oup.com
Objective To review our experience with cabergoline, a D2-selective dopamine agonist, for
the treatment of giant prolactinomas. Design A retrospective case series; descriptive …

Therapy of endocrine disease: the challenges in managing giant prolactinomas

D Maiter, E Delgrange - European Journal of Endocrinology, 2014 - academic.oup.com
Giant prolactinomas are rare tumours, representing only 2–3% of all prolactin (PRL)-
secreting tumours and raising special diagnostic and therapeutic challenges. Based on …

Giant prolactinoma in men: clinical features and therapeutic outcomes

P Iglesias, K Arcano, VR Berrocal… - Hormone and …, 2018 - thieme-connect.com
The aim of the study was to evaluate the clinical features and long-term therapeutic outcome
of giant prolactinoma (gPRLoma) in men and to compare them with those of a group of male …

Giant prolactinomas

I Shimon - Neuroendocrinology, 2019 - karger.com
Prolactin-secreting adenomas (prolactinomas) are the most common secreting adenomas of
the pituitary. Microprolactinomas (diameter< 10 mm) are frequently diagnosed in women …