HTLV-2 Enhances CD8+ T Cell-Mediated HIV-1 Inhibition and Reduces HIV-1 Integrated Proviral Load in People Living with HIV-1

M Abad-Fernández, FJ Hernández-Walias… - Viruses, 2022 - mdpi.com
People living with HIV-1 and HTLV-2 concomitantly show slower CD4+ T cell depletion and
AIDS progression, more frequency of the natural control of HIV-1, and lower mortality rates …

Concluding Remarks for Special Issue HTLV-HIV Co-Infections

A Vallejo, M Abad-Fernández - Viruses, 2023 - mdpi.com
During the early 1980s, the first 3 human retroviruses were identified: human T-lymphotropic
virus 1 and 2 (HTLV-1 and HTLV-2) and human immunodeficiency virus (HIV). A person …

HTLV-II down-regulates HIV-1 replication in IL-2–stimulated primary PBMC of coinfected individuals through expression of MIP-1α

C Casoli, E Vicenzi, A Cimarelli… - Blood, The Journal …, 2000 - ashpublications.org
The influence of human T-cell leukemia/lymphoma virus type II (HTLV-II) in individuals also
infected with HIV-1 is poorly understood. To evaluate the reciprocal influence of HTLV-II and …

HTLV-1/-2 and HIV-1 co-infections: retroviral interference on host immune status

E Pilotti, MV Bianchi, A De Maria, F Bozzano… - Frontiers in …, 2013 - frontiersin.org
The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but
cause significantly different diseases. In this review we have outlined the immune mediated …

Influence of human T cell Lymphotropic virus type 2 coinfection on virological and immunological parameters in HIV type 1–infected patients

S Bassani, M López, C Toro, V Jimenez… - Clinical infectious …, 2007 - academic.oup.com
Background. Human T cell lymphotropic virus type 2 (HTLV-2) infection is not rare among
injection drug users with human immunodeficiency virus (HIV) infection and may exert a …

Co-infection with HTLV-1 is associated with a shorter survival time for HIV-1-infected patients in Bahia, Brazil

C Brites, R Alencar, R Gusmão, C Pedroso, EM Netto… - Aids, 2001 - journals.lww.com
Co-infection with HTLV-1 reaches 20% among patients infected by HIV-1 in Bahia, Brazil. To
evaluate its impact on survival, we conducted a retrospective, case–control study involving …

TLR7/9 antagonist reduces HIV-1-induced immune activation

J Chang, RJ Lindsay, EH Doyle, V Vrbanac, EN Seung… - Retrovirology, 2012 - Springer
Background T cell immune activation is a strong predictor of HIV-1 disease progression and
HIV-1 transmission, and IFN-alpha production following TLR7 stimulation has been …

HIV/HTLV-1 co-infection: a systematic review of current evidence

E Shahmohamadi, SA SeyedAlinaghi… - HIV & AIDS Review …, 2021 - termedia.pl
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) infection is associated with
myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T cell leukemia/lymphoma …

[PDF][PDF] Molecular and cellular interactions of HIV-1/HTLV coinfection and impact on AIDS progression

C Casoli, E Pilotti, U Bertazzoni - Aids Rev, 2007 - academia.edu
In the last 10 years HIV-1/human T-cell leukemia virus (HIV-1/HTLV) coinfection has
emerged as a worldwide health problem. The numbers of HIV-1/HTLV-1 coinfections in …

HIV Type 1 Infection Up-Regulates TLR2 and TLR4 Expression and Function in Vivo and in Vitro

JC Hernández, M Stevenson, E Latz… - AIDS research and …, 2012 - liebertpub.com
Toll-like receptors (TLRs) play a critical role in innate immunity against pathogens. Their
stimulation induces the activation of NF-κB, an important inducer of HIV-1 replication. In …