There is a broad phenotypic spectrum of monogenic polycystic kidney diseases (PKD).
These disorders often involve cilia-related genes and lead to the development of fluid-filled …

Early and severe forms of polycystic kidney disease (PKD) do already manifest during
childhood or adolescence. They are characterized by enlarged kidneys and diminished …

Autosomal dominant hereditary polycystic kidney disease (ADPKD) is the most common
inherited kidney disease that causes end‐stage renal disease and kidney failure …

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common
hereditary forms of chronic kidney disease. Mutations within PKD1 or PKD2 lead to …

Hereditary cystic kidney diseases are considered as “ciliopathies” caused by abnormalities
of the “primary cilia” situated on the tubules. As a result of dysplasia and dysfunction of cilia …

Polycystic kidney disease (PKD) is a group of monogenic disorders that result in renal cyst
development, progressive chronic kidney disease, and are associated with extrarenal …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease and presents with genetic and clinical heterogeneity. ADPKD can also …

Autosomal dominant polycystic kidney disease (ADPKD; MIM 173990) is the most common
hereditary renal disease occurring in 1: 400 to 1: 1000 individuals. It accounts for over 90 …

Murphy et al 1 state that patients with autosomal dominant polycystic kidney disease
(ADPKD) of childbearing potential could benefit from preimplantation genetic diagnosis …

Renal cystic disease and associated ciliopathies : Current Opinion in Obstetrics and
Gynecology Renal cystic disease and associated ciliopathies : Current Opinion in Obstetrics …