Streptococcus suis DNase SsnA contributes to degradation of neutrophil extracellular traps (NETs) and evasion of NET-mediated antimicrobial activity

N de Buhr, A Neumann, N Jerjomiceva… - …, 2014 - microbiologyresearch.org
Streptococcus suis is an important cause of different pathologies in pigs and humans, most
importantly fibrinosuppurative meningitis. Tissue infected with this pathogen is substantially …

Neutrophil extracellular trap formation in the Streptococcus suis‐infected cerebrospinal fluid compartment

N de Buhr, F Reuner, A Neumann… - Cellular …, 2017 - Wiley Online Library
Streptococcus suis is an important meningitis‐causing pathogen in pigs and humans.
Neutrophil extracellular traps (NETs) have been identified as host defense mechanism …

Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis

M Meurer, S Öhlmann, MC Bonilla… - International journal of …, 2020 - mdpi.com
Streptococcus suis is a zoonotic agent causing meningitis in pigs and humans. Neutrophils,
as the first line of defense against S. suis infections, release neutrophil extracellular traps …

Identification of a novel DNase of Streptococcus suis (EndAsuis) important for neutrophil extracellular trap degradation during exponential growth

N de Buhr, M Stehr, A Neumann, HY Naim… - …, 2015 - microbiologyresearch.org
The porcine and human pathogen Streptococcus suis induces and degrades neutrophil
extracellular traps (NETs) in vitro. In this study, we investigated the working hypothesis that …

Extracellular nucleases of Streptococcus equi subsp. zooepidemicus degrade neutrophil extracellular traps and impair macrophage activity of the host

F Ma, X Guo, H Fan - Applied and environmental microbiology, 2017 - Am Soc Microbiol
The pathogen Streptococcus equi subsp. zooepidemicus is associated with a wide range of
animals, including humans, and outbreaks frequently occur in pigs, equines, and goats …

Streptococcus Suis Serotype 2 Stimulates Neutrophil Extracellular Traps Formation via Activation of p38 MAPK and ERK1/2

F Ma, X Chang, G Wang, H Zhou, Z Ma, H Lin… - Frontiers in …, 2018 - frontiersin.org
Streptococcus suis serotype 2 is a major pathogen of swine streptococcicosis, which result
in serious economic loss worldwide. SS2 is an important zoonosis causing meningitis and …

[HTML][HTML] Streptococcus suis Serotype 2 Biofilms Inhibit the Formation of Neutrophil Extracellular Traps

F Ma, L Yi, N Yu, G Wang, Z Ma, H Lin… - Frontiers in cellular and …, 2017 - frontiersin.org
Invasive infections caused by Streptococcus suis serotype 2 (SS2) has emerged as a clinical
problem in recent years. Neutrophil extracellular traps (NETs) are an important mechanism …

Streptococcus suis serotype 2 strains can induce the formation of neutrophil extracellular traps and evade trapping

J Zhao, S Pan, L Lin, L Fu, C Yang, Z Xu… - FEMS Microbiology …, 2015 - academic.oup.com
Streptococcus suis (S. suis) ranks among the five most important porcine pathogens
worldwide and occasionally threatens human health, especially in people that come into …

Phagocytosis and killing of Streptococcus suis by porcine neutrophils

G Chabot-Roy, P Willson, M Segura, S Lacouture… - Microbial …, 2006 - Elsevier
Streptococcus suis serotype 2 is an important swine pathogen responsible for diverse
infections, mainly meningitis. Virulence factors and the pathogenesis of infection are not well …

Nuclease A (Gbs0661), an extracellular nuclease of Streptococcus agalactiae, attacks the neutrophil extracellular traps and is needed for full virulence

A Derré‐Bobillot, NG Cortes‐Perez… - Molecular …, 2013 - Wiley Online Library
Most bacteria of the genus S treptococcus are opportunistic pathogens, and some of them
produce extracellular DNases, which may be important for virulence. Genome analyses of S …