Decreased neurogenesis after cholinergic forebrain lesion in the adult rat

CM Cooper‐Kuhn, J Winkler… - Journal of neuroscience …, 2004 - Wiley Online Library
Adult neurogenesis has been shown to be regulated by a multitude of extracellular cues,
including hormones, growth factors, and neurotransmitters. The cholinergic system of the …

Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb

N Kaneko, H Okano, K Sawamoto - Genes to Cells, 2006 - Wiley Online Library
Neurogenesis in the subgranular zone of the hippocampal dentate gyrus and olfactory bulbs
continues into adulthood and has been implicated in the cognitive function of the adult brain …

Selective immunolesioning of the basal forebrain cholinergic system disrupts short‐term memory in rats

G Leanza, J Muir, OG Nilsson, RG Wiley… - European Journal of …, 1996 - Wiley Online Library
Selective depletion of nerve growth factor receptor‐bearing neurons in the basal forebrain
cholinergic nuclei by the immunotoxin 192 IgG‐saporin offers a new and highly useful tool …

Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor: modeling the cholinergic degeneration of Alzheimer's disease

RG Wiley, TG Berbos, TL Deckwerth… - Journal of the …, 1995 - Elsevier
Degeneration of cholinergic neurons in the basal forebrain (CBF) is a prominent
neuropathological feature of Alzheimer's disease and is thought responsible for some …

Rapid transneuronal degeneration and death of cortical neurons following removal of the olfactory bulb in adult rats

L Heimer, R Kalil - Journal of Comparative Neurology, 1978 - Wiley Online Library
Following olfactory bulb removal in young and adult rats, many neurons in the primary
olfactory cortex become markedly argyrophilic in silver impregnated preparations. Although …

Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury—I. Degeneration and …

T Arendt, MK Brückner, S Pagliusi, T Krell - Neuroscience, 1995 - Elsevier
The process of degeneration and dendritic reorganization of cholinergic neurons was
investigated in the rat basal forebrain under the conditions of chronic neurotoxic injury …

Cognitive and neurological deficits induced by early and prolonged basal forebrain cholinergic hypofunction in rats

L Ricceri, L Minghetti, A Moles, P Popoli… - Experimental …, 2004 - Elsevier
In the present study we examined the long-term effects of neonatal lesion of basal forebrain
cholinergic neurons induced by intracerebroventricular injections of the immunotoxin 192 …

Neonatal lesions of the basal forebrain cholinergic neurons result in abnormal cortical development

CF Hohmann, AR Brooks, JT Coyle - Developmental Brain Research, 1988 - Elsevier
The effect of electrolytic lesions of the neonatal forebrain on the morphogenesis of the
mouse neocortex has been examined. Balb/C mice were lesioned unilaterally within 24 h of …

Proliferation, migration and differentiation of neuronal progenitor cells in the adult mouse subventricular zone surgically separated from its olfactory bulb

A Jankovski, C Garcia, E Soriano… - European Journal of …, 1998 - Wiley Online Library
The subventricular zone of the adult mammalian forebrain contains progenitor cells that, by
migrating along a restricted pathway called the 'rostral migratory stream'(RMS), add new …

Suppression of adult neurogenesis increases the acute effects of kainic acid

SS Iyengar, JJ LaFrancois, D Friedman, LJ Drew… - Experimental …, 2015 - Elsevier
Adult neurogenesis, the generation of new neurons in the adult brain, occurs in the
hippocampal dentate gyrus (DG) and the olfactory bulb (OB) of all mammals, but the …