miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

MicroRNAs regulate cell cycle and cell death pathways in glioblastoma

ISEE Sati, I Parhar - International journal of molecular sciences, 2021 - mdpi.com
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its
resistance to the current treatment regimen. Over the last few decades, a significant amount …

[HTML][HTML] Role of microRNAs in glioblastoma

M Chen, Z Medarova, A Moore - Oncotarget, 2021 - ncbi.nlm.nih.gov
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …

Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy

A Nikaki, C Piperi, AG Papavassiliou - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Gliomas consist of a very heterogeneous group of malignant tumors,
accounting for 50–60% of primary brain tumors. Despite all the efforts of cytoreductive …

MicroRNAs in glioblastoma pathogenesis and therapy: A comprehensive review

BK Ahir, H Ozer, HH Engelhard, SS Lakka - Critical Reviews in Oncology …, 2017 - Elsevier
Glioblastoma (GBM), also known as grade IV astrocytoma, is the most aggressive primary
intracranial tumor of the adult brain. MicroRNAs (miRNAs), a class of small non-coding RNA …

The role of miRNAs in angiogenesis, invasion and metabolism and their therapeutic implications in gliomas

S Beyer, J Fleming, W Meng, R Singh, SJ Haque… - Cancers, 2017 - mdpi.com
MicroRNAs (miRNAs) are small, non-coding, endogenous RNA molecules that function in
gene silencing by post-transcriptional regulation of gene expression. The dysregulation of …

Oncogenic role of microRNAs in brain tumors

JC Pang, WK Kwok, Z Chen, HK Ng - Acta neuropathologica, 2009 - Springer
MicroRNAs (miRNAs) are short non-protein-coding RNAs that function as key regulators of
diverse biological processes through negative control on gene expression at the post …

microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

Recent insights into the microRNA-dependent modulation of gliomas from pathogenesis to diagnosis and treatment

A Mafi, A Rahmati, Z Babaei Aghdam, R Salami… - Cellular & Molecular …, 2022 - Springer
Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …