Trypsinogen activation can be quantified by measurement of released activation peptides
(TAP assay). TAP assay in urine was performed on admission for 55 patients with acute …

Background There is a pressing clinical requirement for an early simple test of severity in
acute pancreatitis. We investigated the use of an assay of trypsinogen activation peptide …

OBJECTIVE: The management of patients with acute pancreatitis is complicated by the
inability to distinguish mild from severe disease during the early stages. It has been …

Acute pancreatitis is a common digestive disease which is usually diagnosed when there is
acute abdominal pain associated with a concomitant rise of serum amylase and lipase …

Conclusions Urinary TAP obtained within the first 48 h of the onset of symptoms can
distinguish patients with severe acute pancreatitis. Background Urinary trypsinogen …

Background A simple, rapid test that is specific and sensitive enough to distinguish, in
patients with clinically suspected acute pancreatitis, those whose abdominal pain is indeed …

Background: Early prediction of severity is important in the management of patients with
acute pancreatitis. The presence of activation peptides and certain pancreatic proenzymes …

Intrapancreatic activation of trypsinogens is believed to occur either as a cause or a
consequence of acute pancreatitis and to be associated with the more severe forms of the …

Background: Early identification of patients at risk of developing a severe attack of acute
pancreatitis (AP) is of great importance because rapid therapeutic interventions improve …

We examined the clinical utility of urine trypsinogen-2 as a marker of acute pancreatitis (AP).
Fifty-nine patients with AP, 42 with acute abdominal diseases of extrapancreatic origin, and …