In atherosclerosis, macrophages are important for intracellular lipid accumulation and foam
cell formation. Monocytes respond to chemotactic factors, cytokines, and macrophage …

A wide variety of cell populations, including both immune and endothelial cells, participate in
the pathogenesis of atherosclerosis. Among these groups, macrophages deserve special …

Atherosclerosis is a chronic inflammatory disease characterized by lipid accumulation and
plaque formation in arterial vessel walls. Atherosclerotic plaques narrow the arterial lumen …

Atherosclerosis is a chronic inflammatory disease that may ultimately lead to local
proteolysis, plaque rupture, and thrombotic vascular disease, resulting in myocardial …

Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …

Monocyte-derived macrophages and foam cells play a central role in atherogenesis. In vitro
studies suggest that macrophages exhibit many functions relevant to lesion initiation …

Atherosclerosis is a pathological process that takes place in the major arteries and is the
underlying cause of heart attacks, stroke and peripheral artery disease. The earliest …

Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …

Atherosclerosis is a chronic immune-inflammatory disease in which the interactions of
monocytes with activated endothelium are crucial events leading to atherosclerotic alteration …