Background Worldwide, gastric cancer (GC) is the fourth most common malignancy and the
most common cancer in East Asia. Development of targeted therapies for this disease has …

Fibroblast growth factor receptor type 2 (FGFR2) has emerged as a key oncogenic factor that
regulates gastric cancer (GC) progression, but the underlying mechanism of FGF–FGFR2 …

The Wnt signaling pathway is evolutionarily conserved, regulating both embryonic
development and maintaining adult tissue homeostasis. Wnt signaling controls several …

Gastric cancer is the second most common cause of cancer-related death in the world,
representing a major global health issue. The high mortality rate is largely due to the lack of …

Gastric adenocarcinoma is a highly aggressive disease with poor overall survival. The
aggressive nature of this disease is in part due to the high intra and inter tumoral …

Gastric cancer, a highly invasive and aggressive malignancy, is the third leading cause of
death from cancer worldwide. Genetic association studies have successfully revealed …

Background Gastric cancer (GC) is the fourth leading cause of cancer-related death
worldwide. However, the precise mechanisms and specific biomarkers of GC have not been …

Gastrointestinal adenocarcinomas (GIAC) of the tubular gastrointestinal (GI) tract including
esophagus, stomach, colon, and rectum comprise most GI cancers and share a spectrum of …

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. Recent
high-throughput analyses of genomic alterations revealed several driver genes and altered …

Background. Construction of the transcriptional regulatory network can provide additional
clues on the regulatory mechanisms and therapeutic applications in gastric cancer …