… We also found that CD8 + T cells are predominantly … Isolation of CD8 + T cells from the
lesional skin of early active … and together strongly suggest that CD8 + T cells contribute to SSc …

… subtype of CD4 + CD8 + double-positive T cells in the skin of … + CD8 + double-positive T
cells, CD8 + single-positive T cells … This increase in CD8 + single-positive T-cell IL-4 secretion …

… CD8 + T cells (Fig. 1a). While very little IL-4 production was detected in the culture supernatants
of CD4 + and CD8 + T cells … in CD4 and/or CD8 T cells by intracellular cytokine staining (…

… We purified CD8+CD45RA+ T cells from total CD8+ T cells isolated from SSc patients and …
-13+ cells in the CD45RA+ (naive and effector) and CD45RA– (memory) CD8+ T cell subsets (…

… circulating CD8 + T cells to migrate to sites of evolving scleroderma … in scleroderma tissue
to attract mononuclear blood cells [… ahead with IFNγ production in CD8 + T cells, which was in …

… Fibrosis is a major contributor to morbidity and mortality in systemic sclerosis (SSc). T cells
… ) production by peripheral blood effector CD8+ T cells from SSc patients correlates with the …

… In this study, we first purified effector memory CD8 + T cells by cell sorting and subsequently
performed cDNA microarray analysis of the sort-purified effector memory CD8 + T cells from …

… in MICs, T cell subsets (CD4/CD8), and … and CD8 T cell counts are seen in the BALF, blood,
and skin of patients with SSc; and (5) there is a significant correlation between CD8+ T cell …

… Here we analyzed the role of CD8 + CD28 – T cells in the pathogenesis of systemic sclerosis
(… Thus, our findings indicate that CD8 + CD28 – T cells represent a pathogenic T-cell subset …

… the DNA methylome in primary T cells of patients with systemic sclerosis. Genome-wide DNA
methylation assays of CD4 + and CD8 + T cells from 24 systemic sclerosis patients and 24 …