Toxicological characteristics of nanoparticulate anatase titanium dioxide in mice

Y Duan, J Liu, L Ma, N Li, H Liu, J Wang, L Zheng… - Biomaterials, 2010 - Elsevier
In an effort to examine liver injury, immune response, and other physiological effects in mice
caused by intragastric administration of nanoparticulate anatase titanium dioxide (5nm), we …

Oxidative stress in the brain of mice caused by translocated nanoparticulate TiO2 delivered to the abdominal cavity

L Ma, J Liu, N Li, J Wang, Y Duan, J Yan, H Liu… - Biomaterials, 2010 - Elsevier
In order to study the mechanisms underlying the effects of TiO2 nanoparticles on the brain,
ICR mice were injected with nanoparticulate anatase TiO2 (5nm) of various doses into the …

Cardiac oxidative damage in mice following exposure to nanoparticulate titanium dioxide

L Sheng, X Wang, X Sang, Y Ze, X Zhao… - … Research Part A, 2013 - Wiley Online Library
Nanoparticulate titanium dioxide (nano‐TiO2) is a widely used powerful nanoparticulate
material with high stability, anticorrosion, and photocatalytic property. However, it is possible …

[PDF][PDF] Oral toxic exposure of titanium dioxide nanoparticles on serum biochemical changes in adult male Wistar rats.

D Vasantharaja, V Ramalingam, GA Reddy - Nanomedicine journal, 2015 - sid.ir
Abstract Objective (s): Titanium dioxide (TiO2) nanoparticles (NPs) are widely used in
commercial food additives and cosmetics worldwide. Uptake of these nanoparticulate into …

Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration

J Wang, G Zhou, C Chen, H Yu, T Wang, Y Ma, G Jia… - Toxicology letters, 2007 - Elsevier
In order to evaluate the toxicity of TiO2 particles, the acute toxicity of nano-sized TiO2
particles (25 and 80nm) on adult mice was investigated compared with fine TiO2 particles …

Histologic and apoptotic changes induced by titanium dioxide nanoparticles in the livers of rats

S Alarifi, D Ali, AA Al-Doaiss, BA Ali… - International journal …, 2013 - Taylor & Francis
Titanium dioxide (TiO2) nanoparticles are among the top five nanoparticles used in
consumer products, paints, and pharmaceutical preparations. Given that exposure to such …

Spleen injury and apoptotic pathway in mice caused by titanium dioxide nanoparticules

N Li, Y Duan, M Hong, L Zheng, M Fei, X Zhao, J Wang… - Toxicology letters, 2010 - Elsevier
Nanoparticulate titanium dioxide (TiO2) has been demonstrated to decrease immunity of
mice, but very little is known about the injury of spleen involved immunomodulation and its …

[HTML][HTML] Acute toxicity of intravenously administered titanium dioxide nanoparticles in mice

J Xu, H Shi, M Ruth, H Yu, L Lazar, B Zou, C Yang… - PloS one, 2013 - journals.plos.org
Background With a wide range of applications, titanium dioxide (TiO2) nanoparticles (NPs)
are manufactured worldwide in large quantities. Recently, in the field of nanomedicine …

The chronic spleen injury of mice following long‐term exposure to titanium dioxide nanoparticles

X Sang, L Zheng, Q Sun, N Li, Y Cui… - … research Part A, 2012 - Wiley Online Library
To understand the chronic spleen injury induced by intragastric administrations with 2.5, 5,
and 10 mg kg− 1 body weight titanium dioxide nanoparticles (TiO2 NPs) for 90 consecutive …

Inflammatory response of mice to manufactured titanium dioxide nanoparticles: comparison of size effects through different exposure routes

VH Grassian, A Adamcakova-Dodd, JM Pettibone… - …, 2007 - Taylor & Francis
TiO2 is a widely used manufactured nanomaterial and the opportunity for human exposure
makes it necessary to study its health implications. Using murine models for inflammation …