Fucanomics and galactanomics: Current status in drug discovery, mechanisms of action and role of the well-defined structures
VH Pomin - Biochimica et Biophysica Acta (BBA)-General Subjects, 2012 - Elsevier
BACKGROUND: With the recent advent of glycomics, many medically relevant glycans have
been discovered. Sulfated fucans (SFs) and sulfated galactans (SGs) are one of these …
been discovered. Sulfated fucans (SFs) and sulfated galactans (SGs) are one of these …
Marine non-glycosaminoglycan sulfated glycans as potential pharmaceuticals
VH Pomin - Pharmaceuticals, 2015 - mdpi.com
Sulfated fucans (SFs) and sulfated galactans (SGs) are currently the marine non-
glycosaminoglycan (GAG) sulfated glycans most studied in glycomics. These compounds …
glycosaminoglycan (GAG) sulfated glycans most studied in glycomics. These compounds …
Fucanomics and galactanomics: Marine distribution, medicinal impact, conceptions, and challenges
VH Pomin - Marine drugs, 2012 - mdpi.com
Glycomics turned out to be a very extensive project where its subdivision is consequently
emerging. This is seen by the growing number of terminologies used to define subprojects …
emerging. This is seen by the growing number of terminologies used to define subprojects …
Marine medicinal glycomics
VH Pomin - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Glycomics is an international initiative aimed to understand the structure and function of the
glycans from a given type of cell, tissue, organism, kingdom or even environment, as found …
glycans from a given type of cell, tissue, organism, kingdom or even environment, as found …
Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents
Fucoidan is a complex polysaccharide (molecular weight 10,000–100,000 Da) derived from
brown algae which comprises of L-fucose and sulfate groups have potential as therapeutic …
brown algae which comprises of L-fucose and sulfate groups have potential as therapeutic …
Structural and functional insights into sulfated galactans: a systematic review
VH Pomin - Glycoconjugate journal, 2010 - Springer
Sulfated galactans (SGs) are highly anionic marine galactose-composed
homopolysaccharides. Although their structures vary among species, their main features are …
homopolysaccharides. Although their structures vary among species, their main features are …
Sulfated galactofucans: An outstanding class of fucoidans with promising bioactivities
Fucoidans encompass versatile and heterogeneous sulfated biopolysaccharides of marine
origin, specifically brown algae and marine invertebrates. Their chemistry and bioactivities …
origin, specifically brown algae and marine invertebrates. Their chemistry and bioactivities …
Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of …
O Berteau, B Mulloy - Glycobiology, 2003 - academic.oup.com
Sulfated fucans, frequently referred to simply as fucans, constitute a class of polysaccharides
first isolated in 1913. For many years fucans were regarded only as a potential source of l …
first isolated in 1913. For many years fucans were regarded only as a potential source of l …
Structure, biology, evolution, and medical importance of sulfated fucans and galactans
VH Pomin, PAS Mourão - Glycobiology, 2008 - academic.oup.com
Sulfated fucans and galactans are strongly anionic polysaccharides found in marine
organisms. Their structures vary among species, but their major features are conserved …
organisms. Their structures vary among species, but their major features are conserved …
Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives
PAS Mourão - Current Pharmaceutical Design, 2004 - ingentaconnect.com
Sulfated α-L-fucans from brown algae (also known as fucoidan) have complex and
heterogeneous structures but recent studies revealed the occurrence of ordered repeat units …
heterogeneous structures but recent studies revealed the occurrence of ordered repeat units …