Myotubularin-related protein 4 (MTMR4) attenuates BMP/Dpp signaling by dephosphorylation of Smad proteins
J Yu, X He, YG Chen, Y Hao, S Yang, L Wang… - Journal of Biological …, 2013 - ASBMB
Bone morphogenetic proteins (BMPs) signaling essentially regulates a wide range of
biological responses. Although multiple regulators at different layers of the receptor-effectors …
biological responses. Although multiple regulators at different layers of the receptor-effectors …
Myoneurin regulates BMP signaling by competing with Ppm1a for Smad binding
S Yang, G Ning, Y Hou, Y Cao, J Xu, J Wu, T Zhang… - Iscience, 2022 - cell.com
A delicate balance of BMP activity is critical for tissue formation and organogenesis.
However, the mechanical molecular details in ensuring the proper duration and intensity of …
However, the mechanical molecular details in ensuring the proper duration and intensity of …
Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling
H Urrutia, A Aleman, E Eivers - Scientific Reports, 2016 - nature.com
Bone morphogenetic proteins (BMPs) are growth factors that provide essential signals for
normal embryonic development and adult tissue homeostasis. A key step in initiating BMP …
normal embryonic development and adult tissue homeostasis. A key step in initiating BMP …
[HTML][HTML] Arginine methylation initiates BMP-induced Smad signaling
Kinase activation and substrate phosphorylation commonly form the backbone of signaling
cascades. Bone morphogenetic proteins (BMPs), a subclass of TGF-β family ligands, induce …
cascades. Bone morphogenetic proteins (BMPs), a subclass of TGF-β family ligands, induce …
A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor
Bone morphogenetic protein (BMP) signaling regulates many different biological processes,
including cell growth, differentiation, and embryogenesis. BMPs bind to heterogeneous …
including cell growth, differentiation, and embryogenesis. BMPs bind to heterogeneous …
MTMR4 attenuates transforming growth factor β (TGFβ) signaling by dephosphorylating R-Smads in endosomes
J Yu, L Pan, X Qin, H Chen, Y Xu, Y Chen… - Journal of Biological …, 2010 - ASBMB
Homeostasis of Smad phosphorylation at its C-terminal SXS motif is essential for
transforming growth factor β (TGFβ) signaling. Whereas it is known that TGFβ signaling can …
transforming growth factor β (TGFβ) signaling. Whereas it is known that TGFβ signaling can …
Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway
X Duan, YY Liang, XH Feng, X Lin - Journal of Biological Chemistry, 2006 - ASBMB
Bone morphogenetic proteins (BMPs) are secreted polypeptides belonging to the
transforming growth factor-β (TGF-β) superfamily that activates a broad range of biological …
transforming growth factor-β (TGF-β) superfamily that activates a broad range of biological …
Balancing BMP signaling through integrated inputs into the Smad1 linker
G Sapkota, C Alarcón, FM Spagnoli, AH Brivanlou… - Molecular cell, 2007 - cell.com
FGF and other Ras/MAPK pathway activators counterbalance BMP action during
neurogenesis, bone formation, and other aspects of vertebrate development and …
neurogenesis, bone formation, and other aspects of vertebrate development and …
Specific control of BMP signaling and mesenchymal differentiation by cytoplasmic phosphatase PPM1H
Bone morphogenetic proteins (BMPs) belong to the TGF-β superfamily of structurally related
signaling proteins that regulate a wide array of cellular functions. The key step in BMP signal …
signaling proteins that regulate a wide array of cellular functions. The key step in BMP signal …
Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction
R Satow, A Kurisaki, T Chan, TS Hamazaki… - Developmental cell, 2006 - cell.com
Bone morphogenetic proteins (BMPs) regulate multiple biological processes, including
cellular proliferation, adhesion, differentiation, and early development. In Xenopus …
cellular proliferation, adhesion, differentiation, and early development. In Xenopus …