When cell cycle withdrawal accompanies terminal differentiation, biosynthesis and cellular
growth are likely to change also. In this study, nucleolus size was monitored during cell fate …

Global changes in gene expression and exit from the cell cycle underlie differentiation.
Therefore, understanding chromatin behavior in differentiating nuclei and late G1 is key to …

The nucleolus dynamically alters its shape through the assembly and disassembly of a
variety of nucleolar components in proliferating cells. While the nucleolus is known to …

Highly reproducible tissue development is achieved by robust, time-dependent coordination
of cell proliferation and cell death. To study the mechanisms underlying robust tissue growth …

Early embryos must rapidly generate large numbers of cells to form an organism. Many
species accomplish this through a series of rapid, reductive, and transcriptionally silent …

ABSTRACT modulo belongs to the class of Drosophila genes named 'suppressor of position-
effect variegation', suggesting the involvement of the encoded protein in chromatin …

Gene transcription in eukaryotes is regulated through dynamic interactions of a variety of
different proteins with DNA in the context of chromatin. Here, we used mass spectrometry for …

The cell number of the early Drosophila embryo is determined by exactly 13 rounds of
synchronous nuclear divisions, allowing cellularization and formation of the embryonic …

The adult eye is composed of 750-800 ommatidia each consisting of 20 cells. Thus there are
approximately 16,000 viable cells in the adult eye. Approximately 2000 of the cells …

Background The shape of a nucleus depends on the nuclear lamina, which is tightly
associated with the inner nuclear membrane and on the interaction with the cytoskeleton …